TGF-Ý signalling in human skeletal muscle regeneration and diabetes
thesis
posted on 2010-01-01, 00:00authored byRani Watts
The TGF-Ý superfamily comprises a large group of proteins with many effects on muscle growth and maturation. The molecular regulation of skeletal muscle regeneration and metabolism in response to prominent superfamily members, myostatin and TGF-Ý1, were analysed, demonstrating the importance of this pathway in controlling how muscles grow and are regulated.