Vaccinia virus B15R gene : influence on pathogenesis and immunogenicity
thesis
posted on 1999-01-01, 00:00authored byNathan W. Bartlett
Genetically engineered vaccinia viruses are potential candidates for vaccine construction. This study investigated the vaccinia virus B15R gene, which is involved in modulating virulence. Genetically engineered vaccinia viruses were constructed to evaluate the influence of the B15R gene on the ability of these viruses to induce an immune response against a foreign antigen.