Does high-intensity resistance training maintain bone mass during moderate weight loss in older overweight adults with type 2 diabetes?

Daly, Robin, Dunstan, David W., Owen, Neville, Jolley, Damien, Shaw, Jonathan and Zimmet, Paul Z. 2005, Does high-intensity resistance training maintain bone mass during moderate weight loss in older overweight adults with type 2 diabetes?, Osteoporosis international, vol. 16, no. 12, pp. 1703-1712, doi: 10.1007/s00198-005-1906-4.

Attached Files
Name Description MIMEType Size Downloads

Title Does high-intensity resistance training maintain bone mass during moderate weight loss in older overweight adults with type 2 diabetes?
Author(s) Daly, RobinORCID iD for Daly, Robin
Dunstan, David W.
Owen, Neville
Jolley, Damien
Shaw, Jonathan
Zimmet, Paul Z.
Journal name Osteoporosis international
Volume number 16
Issue number 12
Start page 1703
End page 1712
Publisher Springer-Verlag
Place of publication London, England
Publication date 2005-12
ISSN 0937-941X
Keyword(s) bone mineral density
resistance training
type 2 diabetes
weight loss
Summary The aim was to investigate whether the addition of supervised high intensity progressive resistance training to a moderate weight loss program (RT+WLoss) could maintain bone mineral density (BMD) and lean mass compared to moderate weight loss (WLoss) alone in older overweight adults with type 2 diabetes. We also investigated whether any benefits derived from a supervised RT program could be sustained through an additional home-based program. This was a 12-month trial in which 36 sedentary, overweight adults aged 60 to 80 years with type 2 diabetes were randomized to either a supervised gymnasium-based RT+WLoss or WLoss program for 6 months (phase 1). Thereafter, all participants completed an additional 6-month home-based training without further dietary modification (phase 2). Total body and regional BMD and bone mineral content (BMC), fat mass (FM) and lean mass (LM) were assessed by DXA every 6 months. Diet, muscle strength (1-RM) and serum total testosterone, estradiol, SHBG, insulin and IGF-1 were measured every 3 months. No between group differences were detected for changes in any of the hormonal parameters at any measurement point. In phase 1, after 6 months of gymnasium-based training, weight and FM decreased similarly in both groups (P<0.01), but LM tended to increase in the RT+WLoss (n=16) relative to the WLoss (n=13) group [net difference (95% CI), 1.8% (0.2, 3.5), P<0.05]. Total body BMD and BMC remained unchanged in the RT+WLoss group, but decreased by 0.9 and 1.5%, respectively, in the WLoss group (interaction, P<0.05). Similar, though non-significant, changes were detected at the femoral neck and lumbar spine (L2-L4). In phase 2, after a further 6 months of home-based training, weight and FM increased significantly in both the RT+WLoss (n=14) and WLoss (n=12) group, but there were no significant changes in LM or total body or regional BMD or BMC in either group from 6 to 12 months. These results indicate that in older, overweight adults with type 2 diabetes, dietary modification should be combined with progressive resistance training to optimize the effects on body composition without having a negative effect on bone health.
Notes Published online: 4 June 2005
Language eng
DOI 10.1007/s00198-005-1906-4
Field of Research 111716 Preventive Medicine
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2005, International Osteoporosis Foundation and National Osteoporosis Foundation
Persistent URL

Connect to link resolver
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 66 times in TR Web of Science
Scopus Citation Count Cited 73 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 1197 Abstract Views, 0 File Downloads  -  Detailed Statistics
Created: Mon, 07 Jul 2008, 08:43:32 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact