Detection of pyrrolizidine alkaloids using flow analysis with both acidic potassium permanganate and tris(2,2’-bipyridyl)ruthenium(II) chemiluminescence Gorman, Bree, Barnett, Neil and Bos, Richard 2005, Detection of pyrrolizidine alkaloids using flow analysis with both acidic potassium permanganate and tris(2,2’-bipyridyl)ruthenium(II) chemiluminescence, Analytica chimica acta, vol. 541, no. 1-2, pp. 119-124, doi: 10.1016/j.aca.2004.11.055. Attached Files Name Description MIMEType Size Downloads Title Detection of pyrrolizidine alkaloids using flow analysis with both acidic potassium permanganate and tris(2,2’-bipyridyl)ruthenium(II) chemiluminescence Author(s) Gorman, Bree Barnett, Neil Bos, Richard Journal name Analytica chimica acta Volume number 541 Issue number 1-2 Start page 119 End page 124 Publisher Elsevier BV Place of publication Amsterdam, The Netherlands Publication date 2005-06 ISSN 0003-2670 1873-4324 Keyword(s) pyrrolizidine alkaloids chemiluminescence immobilised tris(2,2′-bipyridyl)ruthenium(II) sequential injection Summary For the first time, analytically useful chemiluminescence was elicited from the reactions of the pyrrolizidine alkaloids. Heliotrine, retronecine, supinine, monocrotaline and echinatine N-oxide yielded chemiluminescence upon reaction with tris(2,2′-bipyridyl)ruthenium(II) whilst lasiocarpine, its N-oxide and supinine elicited light upon reaction with acidic potassium permanganate. Detection limits for heliotrine were 1.25 × 10−7 M and 9 × 10−9 M for tris(2,2′-bipyridyl)ruthenium(III) perchlorate with flow injection analysis (FIA) and the silica-immobilised reagent (4-[4-(dichloromethylsilanyl)-butyl]-4′-methyl-2,2′-bipyridine)bis(2,2′-bipyridyl)ruthenium(II) with sequential injection analysis (SIA), respectively. Lasiocarpine was detectable at 1.4 × 10−7 M using acidic potassium permanganate with FIA. Additionally, the silica-immobilised reagent was optimised with respect to the oxidant (ammonium ceric nitrate) concentration and the aspiration times which afforded a detection limit for codeine of 5 × 10−10 M using SIA. Language eng DOI 10.1016/j.aca.2004.11.055 Field of Research 030103 Flow Analysis Socio Economic Objective 970103 Expanding Knowledge in the Chemical Sciences HERDC Research category C1 Refereed article in a scholarly journal Copyright notice ©2004, Elsevier B.V. Persistent URL http://hdl.handle.net/10536/DRO/DU:30003186 Document type: Journal Article Collections: Faculty of Science, Engineering and Built Environment School of Biological and Chemical Sciences Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Mon, 03 Nov 2008, 09:44:17 EST Thu, 04 Jun 2009, 09:39:22 EST Wed, 05 Aug 2009, 14:29:57 EST Wed, 02 Oct 2013, 08:29:39 EST Fri, 13 Jun 2014, 23:09:57 EST Fri, 22 Aug 2014, 14:43:02 EST Filtered Full Citation counts:   Cited 18 times in TR Web of Science Cited 9 times in Scopus Search Google Scholar Access Statistics: 1120 Abstract Views, 1 File Downloads  -  Detailed Statistics Created: Mon, 07 Jul 2008, 08:45:52 EST