Development and application of model of resource utilization, costs, and outcomes for stroke (MORUCOS): an Australian economic model for stroke

Mihalopoulos, Catherine, Cadilhac, Dominique A, Moodie, Marjory L, Dewey, Helen M, Thrift, Amanda G, Donnan, Geoffrey and Carter, Robert C 2005, Development and application of model of resource utilization, costs, and outcomes for stroke (MORUCOS): an Australian economic model for stroke, International journal of technology assessment in health care, vol. 21, no. 4, pp. 499-505, doi: 10.1017/S0266462305050695.

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Title Development and application of model of resource utilization, costs, and outcomes for stroke (MORUCOS): an Australian economic model for stroke
Author(s) Mihalopoulos, CatherineORCID iD for Mihalopoulos, Catherine
Cadilhac, Dominique A
Moodie, Marjory LORCID iD for Moodie, Marjory L
Dewey, Helen M
Thrift, Amanda G
Donnan, Geoffrey
Carter, Robert CORCID iD for Carter, Robert C
Journal name International journal of technology assessment in health care
Volume number 21
Issue number 4
Start page 499
End page 505
Total pages 7
Publisher Cambridge University Press
Place of publication Cambridge, Eng.
Publication date 2005-10
ISSN 0266-4623
Keyword(s) cerebrovascular disorders
economic model
cost benefit analysis
Science & Technology
Life Sciences & Biomedicine
Health Care Sciences & Services
Public, Environmental & Occupational Health
Medical Informatics
Summary Objectives: To outline the development, structure, data assumptions, and application of an Australian economic model for stroke (Model of Resource Utilization, Costs, and Outcomes for Stroke [MORUCOS]).Methods: The model has a linked spreadsheet format with four modules to describe the disease burden and treatment pathways, estimate prevalence-based and incidence-based costs, and derive life expectancy and quality of life consequences. The model uses patient-level, community-based, stroke cohort data and macro-level simulations. An interventions module allows options for change to be consistently evaluated by modifying aspects of the other modules. To date, model validation has included sensitivity testing, face validity, and peer review. Further validation of technical and predictive accuracy is needed. The generic pathway model was assessed by comparison with a stroke subtypes (ischemic, hemorrhagic, or undetermined) approach and used to determine the relative cost-effectiveness of four interventions.Results: The generic pathway model produced lower costs compared with a subtypes version (total average first-year costs/case AUD$15,117 versus AUD$17,786, respectively). Optimal evidence-based uptake of anticoagulation therapy for primary and secondary stroke prevention and intravenous thrombolytic therapy within 3 hours of stroke were more cost-effective than current practice (base year, 1997).Conclusions: MORUCOS is transparent and flexible in describing Australian stroke care and can effectively be used to systematically evaluate a range of different interventions. Adjusting results to account for stroke subtypes, as they influence cost estimates, could enhance the generic model.
Language eng
DOI 10.1017/S0266462305050695
Field of Research 110904 Neurology and Neuromuscular Diseases
1117 Public Health and Health Services
1402 Applied Economics
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2005, Cambridge University Press
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Document type: Journal Article
Collections: Faculty of Health
Population Health
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