Assessing cost-effectiveness in mental health : family interventions for schizophrenia and related conditions

Mihalopoulos, Cathy, Magnus, Anne, Carter, Rob and Vos, Theo 2004, Assessing cost-effectiveness in mental health : family interventions for schizophrenia and related conditions, Australian and New Zealand journal of psychiatry, vol. 38, no. 7, pp. 511-519, doi: 10.1111/j.1440-1614.2004.01404.x.

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Title Assessing cost-effectiveness in mental health : family interventions for schizophrenia and related conditions
Author(s) Mihalopoulos, CathyORCID iD for Mihalopoulos, Cathy
Magnus, AnneORCID iD for Magnus, Anne
Carter, RobORCID iD for Carter, Rob
Vos, Theo
Journal name Australian and New Zealand journal of psychiatry
Volume number 38
Issue number 7
Start page 511
End page 519
Publisher Wiley Interscience
Place of publication Malden, Mass.
Publication date 2004
ISSN 0004-8674
Keyword(s) behaviour therapy
family therapy
Summary Objective: Existing evidence suggests that family interventions can be effective in reducing relapse rates in schizophrenia and related conditions. Despite this, such interventions are not routinely delivered in Australian mental health services. The objective of the current study is to investigate the incremental cost-effectiveness ratios (ICERs) of introducing three types of family interventions, namely: behavioural family management (BFM); behavioural intervention for families (BIF); and multiple family groups (MFG) into current mental health services in Australia.

Method: The ICER of each of the family interventions is assessed from a health sector perspective, including the government, persons with schizophrenia and their families/carers using a standardized methodology. A two-stage approach is taken to the assessment of benefit. The first stage involves a quantitative analysis based on disability-adjusted life years (DALYs) averted. The second stage involves application of 'second filter' criteria (including equity, strength of evidence, feasibility and acceptability to stakeholders) to results. The robustness of results is tested using multivariate probabilistic sensitivity analysis.

Results: The most cost-effective intervention, in order of magnitude, is BIF (A$8000 per DALY averted), followed by MFG (A$21 000 per DALY averted) and lastly BFM (A$28 000 per DALY averted). The inclusion of time costs makes BFM more cost-effective than MFG. Variation of discount rate has no effect on conclusions.

Conclusions: All three interventions are considered 'value-for-money' within an Australian context. This conclusion needs to be tempered against the methodological challenge of converting clinical outcomes into a generic economic outcome measure (DALY). Issues surrounding the feasibility of routinely implementing such interventions need to be addressed.
Notes Published Online: 15 Jul 2004
Language eng
DOI 10.1111/j.1440-1614.2004.01404.x
Field of Research 140208 Health Economics
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2006 The Authors; Journal compilation and The Royal Australian and New Zealand College of Psychiatrists
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Document type: Journal Article
Collections: Faculty of Health
School of Health and Social Development
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