Regional specificity of exercise and calcium during skeletal growth in girls: a randomized controlled trial

Iuliano-Burns, Sandra, Saxon, Leanne, Naughton, Geraldine, Gibbons, Kay and Bass, Shona 2003, Regional specificity of exercise and calcium during skeletal growth in girls: a randomized controlled trial, Journal of bone and mineral research, vol. 18, no. 1, pp. 156-162, doi: 10.1359/jbmr.2003.18.1.156.

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Title Regional specificity of exercise and calcium during skeletal growth in girls: a randomized controlled trial
Author(s) Iuliano-Burns, Sandra
Saxon, Leanne
Naughton, Geraldine
Gibbons, Kay
Bass, Shona
Journal name Journal of bone and mineral research
Volume number 18
Issue number 1
Start page 156
End page 162
Publisher American Society for Bone and Mineral Research
Place of publication Malden, Mass.
Publication date 2003-01
ISSN 0884-0431
Summary Combining exercise with calcium supplementation may produce additive or multiplicative effects at loaded sites; thus, we conducted a single blind, prospective, randomized controlled study in pre- and early-pubertal girls to test the following hypotheses. (1) At the loaded sites, exercise and calcium will produce greater benefits than exercise or calcium alone. (2) At non-loaded sites, exercise will have no benefit, whereas calcium with or without exercise will increase bone mass over that in exercise alone or no intervention. Sixty-six girls aged 8.8 ± 0.1 years were randomly assigned to one of four study groups: moderate-impact exercise with or without calcium or low-impact exercise with or without calcium. All participants exercised for 20 minutes, three times a week and received Ca-fortified (434 ± 19 mg/day) or non-fortified foods for 8.5 months. Analysis of covariance (ANCOVA) was used to determine interaction and main effects for exercise and calcium on bone mass after adjusting for baseline bone mineral content and growth in limb lengths. An exercise-calcium interaction was detected at the femur (7.1%, p < 0.05). In contrast, there was no exercise-calcium interaction detected at the tibia-fibula; however, there was a main effect of exercise: bone mineral content increased 3% more in the exercise than non-exercise groups (p < 0.05). Bone mineral content increased 2-4% more in the calcium-supplemented groups than the non-supplemented groups at the humerus (12.0% vs. 9.8%, respectively, p < 0.09) and radius-ulna (12.6% vs. 8.6%, respectively, p < 0.01). In conclusion, greater gains in bone mass at loaded sites may be achieved when short bouts of moderate exercise are combined with increased dietary calcium, the former conferring region-specific effects and the latter producing generalized effects.
Language eng
DOI 10.1359/jbmr.2003.18.1.156
Field of Research 110604 Sports Medicine
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2003, ASBMR
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Document type: Journal Article
Collections: Faculty of Health
School of Exercise and Nutrition Sciences
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