Live high: train low increases muscle buffer capacity and submaximal cycling efficiency

Gore, C. J., Hahn, A. G., Aughey, R. J., Martin, D. T., Ashenden, M. J., Clark, S. A., Garnham, Andrew, Roberts, A. D., Slater, G. J. and McKenna, M. J. 2001, Live high: train low increases muscle buffer capacity and submaximal cycling efficiency, Acta Physiologica Scandinavica, vol. 173, no. 3, pp. 275-286, doi: 10.1046/j.1365-201X.2001.00906.x.

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Title Live high: train low increases muscle buffer capacity and submaximal cycling efficiency
Author(s) Gore, C. J.
Hahn, A. G.
Aughey, R. J.
Martin, D. T.
Ashenden, M. J.
Clark, S. A.
Garnham, Andrew
Roberts, A. D.
Slater, G. J.
McKenna, M. J.
Journal name Acta Physiologica Scandinavica
Volume number 173
Issue number 3
Start page 275
End page 286
Publisher Wiley Interscience
Place of publication New York, N.Y.
Publication date 2001
ISSN 0001-6772
Keyword(s) altitude training
cycling efficiency
muscle buffering
Summary This study investigated whether hypoxic exposure increased muscle buffer capacity (βm) and mechanical efficiency during exercise in male athletes. A control (CON, n=7) and a live high:train low group (LHTL, n=6) trained at near sea level (600 m), with the LHTL group sleeping for 23 nights in simulated moderate altitude (3000 m). Whole body oxygen consumption (V˙O2) was measured under normoxia before, during and after 23 nights of sleeping in hypoxia, during cycle ergometry comprising 4×4-min submaximal stages, 2-min at 5.6 ± 0.4 W kg–1, and 2-min 'all-out' to determine total work and V˙O2peak. A vastus lateralis muscle biopsy was taken at rest and after a standardized 2-min 5.6 ± 0.4 W kg–1 bout, before and after LHTL, and analysed for βm and metabolites. After LHTL, βm was increased (18%, P < 0.05). Although work was maintained, V˙O2peak fell after LHTL (7%, P < 0.05). Submaximal V˙O2 was reduced (4.4%, P < 0.05) and efficiency improved (0.8%, P < 0.05) after LHTL probably because of a shift in fuel utilization. This is the first study to show that hypoxic exposure, per se, increases muscle buffer capacity. Further, reduced V˙O2 during normoxic exercise after LHTL suggests that improved exercise efficiency is a fundamental adaptation to LHTL.

Notes Published Online: 9 Oct 2008
Language eng
DOI 10.1046/j.1365-201X.2001.00906.x
Field of Research 110602 Exercise Physiology
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2001, Scandinavian Physiological Society
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Document type: Journal Article
Collections: Faculty of Health
School of Health Sciences
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