Cost-effectiveness of a family-based GP-mediated intervention targeting overweight and moderately obese children Moodie, M., Haby, M., Wake, M., Gold, L. and Carter, R. 2008, Cost-effectiveness of a family-based GP-mediated intervention targeting overweight and moderately obese children, Economics and human biology, vol. 6, no. 3, pp. 363-376, doi: 10.1016/j.ehb.2008.06.001. Attached Files Name Description MIMEType Size Downloads Title Cost-effectiveness of a family-based GP-mediated intervention targeting overweight and moderately obese children Author(s) Moodie, M. orcid.org/0000-0001-6890-5250 Haby, M. Wake, M. Gold, L. orcid.org/0000-0002-2733-900X Carter, R. orcid.org/0000-0002-1586-5619 Journal name Economics and human biology Volume number 6 Issue number 3 Start page 363 End page 376 Total pages 14 Publisher Elsevier BV Place of publication Amsterdam, The Netherlands Publication date 2008-12 ISSN 1570-677X 1873-6130 Keyword(s) children overweight general practitioners family-based Summary Objective  To assess from a societal perspective the incremental cost-effectiveness of a family-based GP-mediated intervention targeting overweight and moderately obese children. The intervention was modelled on the LEAP (live, eat and play) trial, a randomised controlled trial conducted by the Centre for Community Child Health, Melbourne, Australia in 2002–2003. This study was undertaken as part of the assessing cost-effectiveness (ACE) in obesity project which evaluated, using consistent methods, 13 interventions targeting unhealthy weight gain in children and adolescents. Method A logic pathway was used to model the effects of the intervention compared to no intervention on body mass index (BMI) and health outcomes (disability-adjusted life years—DALYs). Disease costs and health benefits were tracked until the cohort of eligible children reached the age of 100 years or death. Simulation-modelling techniques were used to present a 95% uncertainty interval around the cost-effectiveness ratio. The intervention was also assessed against a series of filters (‘equity’, ‘strength of evidence’, ‘acceptability’, ‘feasibility’, sustainability’ and ‘side-effects’) to incorporate additional factors that impact on resource allocation decisions. Results The intervention, as modelled, reached 9685 children aged 5–9 years with a BMI z-score of ≥3.0, and cost $AUD6.3M (or $AUD4.8M excluding time costs). It resulted in an incremental saving of 2300 BMI units which translated to 511 DALYs. The cost-offsets stemming from the intervention totalled $AUD3.6M, resulting in a net cost per DALY saved of $AUD4670 (dominated; $0.1M) (dominated means intervention costs more for less effect). Conclusion Compared to a ‘no intervention’ control group, the intervention was cost-effective under current assumptions, although the uncertainty intervals were wide. A key question related to the long-term sustainability of the small incremental weight loss reported, based on the 9-month follow-up results for LEAP. Language eng DOI 10.1016/j.ehb.2008.06.001 Field of Research 110706 Immunogenetics (incl Genetic Immunology) Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category C1 Refereed article in a scholarly journal HERDC collection year 2008 Copyright notice ©2008, Elsevier B.V. Persistent URL http://hdl.handle.net/10536/DRO/DU:30017351 Document type: Journal Article Collections: Faculty of Health Public Health Research, Evaluation, and Policy Cluster Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Fri, 14 Aug 2009, 13:52:24 EST Tue, 13 Oct 2009, 10:38:49 EST Tue, 13 Oct 2009, 10:39:38 EST Mon, 07 Jul 2014, 14:15:06 EST Mon, 07 Jul 2014, 14:18:13 EST Fri, 19 Sep 2014, 10:51:41 EST Filtered Full Citation counts:   Cited 31 times in TR Web of Science Cited 33 times in Scopus Search Google Scholar Access Statistics: 930 Abstract Views, 4 File Downloads  -  Detailed Statistics Created: Fri, 14 Aug 2009, 13:52:24 EST

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