Optimal immune responses : immunocompetence revisited

Viney, Mark E., Riley, Eleanor M. and Buchanan, Katherine L. 2005, Optimal immune responses : immunocompetence revisited, Trends in ecology and evolution, vol. 20, no. 12, pp. 665-669, doi: 10.1016/j.tree.2005.10.003.

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Title Optimal immune responses : immunocompetence revisited
Author(s) Viney, Mark E.
Riley, Eleanor M.
Buchanan, Katherine L.ORCID iD for Buchanan, Katherine L. orcid.org/0000-0002-6648-5819
Journal name Trends in ecology and evolution
Volume number 20
Issue number 12
Start page 665
End page 669
Publisher Elsevier Ltd.
Place of publication London, England
Publication date 2005-12
ISSN 0169-5347
Summary The function of the immune system of an animal is to provide defence against infection, in order to maximize fitness. Understanding this and, particularly, how limiting resources are traded off between costly immune responses and other physiological demands, is central to properly understanding life-history traits and their evolution. Here, we propose that functional (rather than immunological) measures of immune responses should be used when investigating this. We further suggest that optimal immune responses are context specific, rather than generic; that is, a maximum immune response is not necessarily optimal. The nature of an optimal immune response will depend on the specific circumstances and infection status of the animal. Identifying and understanding such optimality requires that the effects of different immune strategies on fitness be considered.
Language eng
DOI 10.1016/j.tree.2005.10.003
Field of Research 060399 Evolutionary Biology not elsewhere classified
Socio Economic Objective 970106 Expanding Knowledge in the Biological Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2005, Elsevier Ltd
Persistent URL http://hdl.handle.net/10536/DRO/DU:30020170

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