The bipolar depression rating scale (BDRS) : its development, validation and utility

Berk, Michael, Malhi, Gin S., Cahill, Catherine, Carman, A. Catherine, Hadzi-Pavlovic, Dusan, Hawkins, Mary T., Tohen, Mauricio and Mitchell, Philip B 2007, The bipolar depression rating scale (BDRS) : its development, validation and utility, Bipolar disorders, vol. 9, no. 6, pp. 571-579, doi: 10.1111/j.1399-5618.2007.00536.x.

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Title The bipolar depression rating scale (BDRS) : its development, validation and utility
Author(s) Berk, MichaelORCID iD for Berk, Michael
Malhi, Gin S.
Cahill, Catherine
Carman, A. Catherine
Hadzi-Pavlovic, Dusan
Hawkins, Mary T.
Tohen, Mauricio
Mitchell, Philip B
Journal name Bipolar disorders
Volume number 9
Issue number 6
Start page 571
End page 579
Publisher Wiley-Blackwell Munksgaard
Place of publication Copenhagen, Denmark
Publication date 2007
ISSN 1398-5647
Keyword(s) assessment
bipolar depression
bipolar disorder
mixed states
rating scale
Summary Objectives: Unipolar and bipolar depression differ neurobiologically and in clinical presentation. Existing depression rating instruments, used in bipolar depression, fail to capture the necessary phenomenological nuances, as they are based on and skewed towards the characteristics of unipolar depression. Both clinically and in research there is a growing need for a new observer-rated scale that is specifically designed to assess bipolar depression.

: An instrument reflecting the characteristics of bipolar depression was drafted by the authors, and administered to 122 participants aged 18–65 (44 males and 78 females) with a diagnosis of DSM-IV bipolar disorder, who were currently experiencing symptoms of depression. The Bipolar Depression Rating Scale (BDRS) was administered together with the Hamilton Depression Rating Scale (HAM-D), Montgomery Asberg Depression Rating Scale (MADRS) and Young Mania Rating Scale (YMRS).

Results: The BDRS has strong internal consistency (Cronbach's alpha = 0.917), and robust correlation coefficients with the MADRS (r = 0.906) and HAM-D (r = 0.744), and the mixed subscale correlated with the YMRS (r = 0.757). Exploratory factor analysis showed a three-factor solution gave the best account of the data. These factors corresponded to depression (somatic), depression (psychological) and mixed symptom clusters.

Conclusions: This study provides evidence for the validity of the BDRS for the measurement of depression in bipolar disorder. These results suggest good internal validity, provisional evidence of inter-rater reliability and strong correlations with other depression rating scales.
Language eng
DOI 10.1111/j.1399-5618.2007.00536.x
Field of Research 111799 Public Health and Health Services not elsewhere classified
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2007, Blackwell Munksgaard
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Document type: Journal Article
Collections: Faculty of Health
School of Nursing and Midwifery
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