Effects of diets high in whey, soy, red meat and milk protein on body weight maintenance in diet-induced obesity in mice Huang, Xu-Feng, Liu, Yingxu, Rahardjo, Gita L., McLennan, Peter L., Tapsell, Linda C. and Buttemer, William A. 2008, Effects of diets high in whey, soy, red meat and milk protein on body weight maintenance in diet-induced obesity in mice, Nutrition and dietetics, vol. 65, no. S3, pp. S53-S59, doi: 10.1111/j.1747-0080.2008.00262.x. Attached Files Name Description MIMEType Size Downloads Title Effects of diets high in whey, soy, red meat and milk protein on body weight maintenance in diet-induced obesity in mice Author(s) Huang, Xu-Feng Liu, Yingxu Rahardjo, Gita L. McLennan, Peter L. Tapsell, Linda C. Buttemer, William A. Journal name Nutrition and dietetics Volume number 65 Issue number S3 Start page S53 End page S59 Total pages 7 Publisher Wiley Blackwell Publishing Asia Place of publication Milton, Qld Publication date 2008-06 ISSN 1446-6368 1747-0080 Keyword(s) adiponectin energy balance high-protein diet obesity Summary This study examined the effects of different food sources of protein on energy intake, body weight maintenance, and on the responses of plasma leptin, insulin and adiponectin in chronic high-fat diet-induced obese mice. Obesity was induced in 47 mice with a high-fat diet for 20 weeks. They were divided into five diet groups to test the effects of a higher protein proportion (30% energy), achieved at the expense of carbohydrate. For the next eight weeks, four of the groups were fed diets of chow formulated with whey, soy, red meat or milk while the control group continued on their high-fat diet. The results showed that: (i) increasing the protein : carbohydrate ratio (both at 30% energy) in a high-fat diet did not reduce the level of obesity; (ii) the type of protein added, however, did have a significant effect on the level of obesity attained; (iii) whey protein stabilised weight gain the most, had the strongest satiety effects and also stimulated the highest production of adiponectin; and (iv) whey protein also was associated with the lowest insulin values among all proteins tested. Plasma leptin levels were not affected by any of the diets. Dietary fat remains a potent factor in weight management, but the type and amount of protein may also be important through its effects on food intake. In particular, the apparent decreased appetite associated with increased adiponectin in the whey-based high-protein diet may contribute to stabilised body mass in chronic high-fat diet-induced obesity. Language eng DOI 10.1111/j.1747-0080.2008.00262.x Field of Research 110399 Clinical Sciences not elsewhere classified Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category C1.1 Refereed article in a scholarly journal HERDC collection year 2008 Copyright notice ©2008, Wiley Blackwell Publishing Asia Persistent URL http://hdl.handle.net/10536/DRO/DU:30020888 Document type: Journal Article Collections: Faculty of Science, Engineering and Built Environment School of Life and Environmental Sciences Centre for Integrative Ecology Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Mon, 16 Nov 2009, 06:52:34 EST Mon, 16 Nov 2009, 12:44:56 EST Mon, 16 Nov 2009, 12:47:42 EST Wed, 18 Nov 2009, 07:55:46 EST Fri, 10 Jan 2014, 09:23:46 EST Tue, 24 Jun 2014, 13:05:21 EST Tue, 24 Jun 2014, 13:07:09 EST Fri, 27 Jun 2014, 09:03:34 EST Thu, 11 Dec 2014, 16:21:36 EST Thu, 01 Oct 2020, 21:35:09 EST Fri, 22 Jul 2022, 16:36:58 EST Filtered Full Citation counts:   Cited 10 times in TR Web of Science Cited 12 times in Scopus Search Google Scholar Access Statistics: 822 Abstract Views, 1 File Downloads  -  Detailed Statistics Created: Mon, 16 Nov 2009, 06:52:34 EST