Comparative structural analyses of purified glycogen particles from rat liver, human skeletal muscle and commercial preparations
Ryu, Je-Hoon, Drain, Jace, Kim, Jung Hwan, McGee, Sean L., Gray-Weale, Angus, Waddington, Lynne, Parker, Glendon J., Hargreaves, Mark, Yoo, Sang-Ho and Stapleton, David 2009, Comparative structural analyses of purified glycogen particles from rat liver, human skeletal muscle and commercial preparations, International journal of biological macromolecules, vol. 45, no. 5, pp. 478-482, doi: 10.1016/j.ijbiomac.2009.08.006.
Attached Files
Name
Description
MIMEType
Size
Downloads
Title
Comparative structural analyses of purified glycogen particles from rat liver, human skeletal muscle and commercial preparations
International journal of biological macromolecules
Volume number
45
Issue number
5
Start page
478
End page
482
Total pages
5
Publisher
Elsevier BV
Place of publication
Amsterdam, Netherlands
Publication date
2009-12-01
ISSN
0141-8130 1879-0003
Summary
Glycogen is a cellular energy store that is crucial for whole body energy metabolism, metabolic regulation and exercise performance. To understand glycogen structure we have purified glycogen particles from rat liver and human skeletal muscle tissues and compared their biophysical properties with those found in commercial glycogen preparations. Ultrastructural analysis of commercial liver glycogens fails to reveal the classical α-rosette structure but small irregularly shaped particles. In contrast, commercial slipper limpet glycogen consists of β-particles with similar branching and chain lengths to purified rat liver glycogen together with a tendency to form small α-particles, and suggest it should be used as a source of glycogen for all future studies requiring a substitute for mammalian liver glycogen.
Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.