Boron nitride nanotubes : a novel vector for targeted magnetic drug delivery
Ciofani, Gianni, Raffa, Vittoria, Yu, Jun, Chen, Ying, Obata, Yosuke, Takeoka, Shinji, Menciassi, Arianna and Cuschieri, Alfred 2009, Boron nitride nanotubes : a novel vector for targeted magnetic drug delivery, Current nanoscience, vol. 5, no. 1, pp. 33-38.
Attached Files
Name
Description
MIMEType
Size
Downloads
Title
Boron nitride nanotubes : a novel vector for targeted magnetic drug delivery
Whereas several biomedical applications of carbon nanotubes have been proposed, the use of boron nitride nanotubes (BNNTs) in this field has been largely unexplored despite their unique and potentially useful properties. Our group has recently initiated an experimental program aimed at the exploration of the interactions between BNNTs and living cells. In the present paper, we report on the magnetic properties of BNNTs containing Fe catalysts which confirm the feasibility for their use as nanovectors for targeted drug delivery. The magnetisation curves of BNNTs characterised by the present study are typical of superparamagnetic materials with important parameters, including magnetic permeability and magnetic momentum, derived by employing Langevin theory. In-vitro tests have demonstrated the feasibility for influencing the uptake of BNNTs by living cells by exposure to an external magnetic source. A finite element method analysis devised to predict this effect produced predictive data with close agreement with the experimental observations.
Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.