Serum levels of brain-derived neurotrophic factor in schizophrenia on a hypocaloric diet Guimarães, Lísia Rejane, Jacka, Felice N., Gama, Clarissa Severino, Berk, Michael, Leitão-Azevedo, Carmen Lúcia, Belmonte de Abreu, Martha Guerra, Lobato, Maria Inês, Andreazza, Ana Cristina, Ceresér, Keila Maria, Kapczinski, Flávio and Belmonte-de-Abreu, Paulo 2008, Serum levels of brain-derived neurotrophic factor in schizophrenia on a hypocaloric diet, Progress in neuro-psychopharmacology & biological psychiatry, vol. 32, no. 6, pp. 1595-1598, doi: 10.1016/j.pnpbp.2008.06.004. Attached Files Name Description MIMEType Size Downloads Title Serum levels of brain-derived neurotrophic factor in schizophrenia on a hypocaloric diet Author(s) Guimarães, Lísia Rejane Jacka, Felice N. orcid.org/0000-0002-9825-0328 Gama, Clarissa Severino Berk, Michael orcid.org/0000-0002-5554-6946 Leitão-Azevedo, Carmen Lúcia Belmonte de Abreu, Martha Guerra Lobato, Maria Inês Andreazza, Ana Cristina Ceresér, Keila Maria Kapczinski, Flávio Belmonte-de-Abreu, Paulo Journal name Progress in neuro-psychopharmacology & biological psychiatry Volume number 32 Issue number 6 Start page 1595 End page 1598 Total pages 4 Publisher Elsevier Place of publication Amsterdam, The Netherlands Publication date 2008-08-01 ISSN 0278-5846 1878-4216 Keyword(s) BDNF BMI hypocaloric diet neurotrophins schizophrenia Summary Dietary factors influence BDNF in animal studies, but there is no comparable data in clinical populations. We examined the effect of a dietary intervention on BDNF serum levels in 67 DSM-IV schizophrenic outpatients (51 males and 16 females). Two groups were assessed in a cross-sectional study: one on a hypocaloric diet (HD) and the other not on a hypocaloric diet. Weight, height and BMI data were collected concurrently with 5-ml blood sampling of each subject. BDNF levels were measured with a sandwich-ELISA. The blood sample was obtained a minimum of one month after the exposure to dietary intervention. Serum BDNF levels were significantly higher in patients on the HD (p = 0.023). Additional research examining the interaction among patterns of nutritional food behavior and underlying physiopathology may result in insights upon which evidence-based decisions regarding dietary interventions can be made in people identified with major psychiatric disorders, such as schizophrenia. Language eng DOI 10.1016/j.pnpbp.2008.06.004 Field of Research 119999 Medical and Health Sciences not elsewhere classified Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category C1.1 Refereed article in a scholarly journal Copyright notice ©2008, Elsevier Inc. Persistent URL http://hdl.handle.net/10536/DRO/DU:30033157 Document type: Journal Article Collections: Faculty of Health School of Medicine Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Thu, 03 Mar 2011, 07:20:34 EST Tue, 31 May 2011, 12:49:45 EST Tue, 31 May 2011, 12:51:05 EST Mon, 16 Jun 2014, 17:29:48 EST Thu, 11 Dec 2014, 16:57:06 EST Filtered Full Citation counts:   Cited 24 times in TR Web of Science Cited 25 times in Scopus Search Google Scholar Access Statistics: 1040 Abstract Views, 2 File Downloads  -  Detailed Statistics Created: Thu, 03 Mar 2011, 07:20:34 EST