Forearm blood flow in individuals with CHF and age-matched healthy volunteers : a study and historical review
Patterson, Jeremy, Selig, Steve, Toia, Deidre, Bamroongsuk, Voramont and Hare, David 2007, Forearm blood flow in individuals with CHF and age-matched healthy volunteers : a study and historical review, Journal of exercise physiology online, vol. 10, no. 5, pp. 1-15.
This study examined forearm blood flow (FBF) in individuals with chronic heart failure (CHF) at rest, moderate exercise, and following limb occlusion. FBF was measured by venous occlusion plethysmography in CHF patients (n = 43) and healthy age-matched volunteers (n = 8) at rest and during exercise consisting of intermittent isometric hand squeezing at 15, 30, and 45% of maximum voluntary contraction (MVC). Peak vasodilatory capacity was also determined following the release of an occluding arm cuff. FBF was lower in CHF patients during exercise and during peak reactive hyperemia (PRH) compared to healthy volunteers, but there was no significant difference between groups at rest. Peak vasodilatory capacity was significantly higher in healthy volunteers than the CHF group ((30.6 ± 8.6 ml±100 mL-1±min-1 and 18.3 ± 6.9 ml±100 mL-1±min-1, respectively). Local blood flow stimulation in response to exercise or limb occlusion is reduced in individuals with CHF, however, there was no difference in resting flows between the two groups, suggesting vasodilatory medication may restore resting blood flow to healthy values.
Notes
Reproduced with the kind permission of the copyright owner.
Language
eng
Field of Research
119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective
970111 Expanding Knowledge in the Medical and Health Sciences
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