Ribosome inactivating proteins purification from a medicinal plant Puri, Munish 2009, Ribosome inactivating proteins purification from a medicinal plant, in Proceedings of the 10th Anniversary Protein Expression Workshop 2009, The Workshop, [Melbourne, Vic.]. Attached Files Name Description MIMEType Size Downloads Title Ribosome inactivating proteins purification from a medicinal plant Author(s) Puri, Munish orcid.org/0000-0003-2469-3326 Conference name Anniversary Protein Expression Workshop (10th : 2009 : Melbourne, Victoria) Conference location Melbourne, Victoria Conference dates 4-7 Aug. 2009 Title of proceedings Proceedings of the 10th Anniversary Protein Expression Workshop 2009 Editor(s) Lovercz, George Publication date 2009 Publisher The Workshop Place of publication [Melbourne, Vic.] Summary The ribosome inactivating proteins (RIPs) from plants possess RNA N- glycosidase activity that depurinates the major rRNA, thus damaging ribosomes in an irreversible manner and arresting protein synthesis. RIPs are presently classified as rRNA N-glycosidase in the enzyme nomenclature (EC 3.2.2.22) and do exhibit other enzymatic activities such as ribonuclease and deoxyribonuclease activities. RIPs have been shown to manifest abortifacient, anti-tumor, anti-viral and anti-microbial activities. RIPs are detected in some medicinal plants but the yields are insufficient to warrant their availability to conduct clinical trials for therapeutic application. Here, we describe an approach based on “bioprocess development” that may enhance the yield of RIPs and eventually their availability for exploiting their therapeutic potential. Language eng Field of Research 100302 Bioprocessing, Bioproduction and Bioproducts Socio Economic Objective 860105 Nutraceuticals and Functional Foods HERDC Research category E2.1 Full written paper - non-refereed / Abstract reviewed Persistent URL http://hdl.handle.net/10536/DRO/DU:30033632 Document type: Conference Paper Collections: Faculty of Science, Engineering and Built Environment Centre for Biotechnology and Interdisciplinary Sciences (BioDeakin)   Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Wed, 23 Mar 2011, 14:39:05 EST Wed, 30 Mar 2011, 09:04:04 EST Thu, 31 Mar 2011, 11:37:36 EST Thu, 31 Mar 2011, 11:38:44 EST Wed, 30 Nov 2011, 16:27:26 EST Wed, 15 Feb 2012, 13:15:46 EST Wed, 17 Sep 2014, 19:37:11 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 0 times in Scopus Search Google Scholar Access Statistics: 375 Abstract Views, 2 File Downloads  -  Detailed Statistics Created: Wed, 23 Mar 2011, 14:38:58 EST by Munish Puri