Carbon nanotubes for biological and biomedical applications

Yang, Wenrong, Thordarson, Pall, Gooding, J. Justin, Ringer, Simon P. and Braet, Filip 2007, Carbon nanotubes for biological and biomedical applications, Nanotechnology, vol. 18, no. 41, pp. 1-13, doi: 10.1088/0957-4484/18/41/412001.

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Title Carbon nanotubes for biological and biomedical applications
Author(s) Yang, WenrongORCID iD for Yang, Wenrong
Thordarson, Pall
Gooding, J. Justin
Ringer, Simon P.
Braet, Filip
Journal name Nanotechnology
Volume number 18
Issue number 41
Start page 1
End page 13
Publisher Institute of Physics
Place of publication London, England
Publication date 2007-10-17
ISSN 0957-4484
Summary Ever since the discovery of carbon nanotubes, researchers have been exploring their potential in biological and biomedical applications. The recent expansion and availability of chemical modification and bio-functionalization methods have made it possible to generate a new class of bioactive carbon nanotubes which are conjugated with proteins, carbohydrates, or nucleic acids. The modification of a carbon nanotube on a molecular level using biological molecules is essentially an example of the 'bottom-up' fabrication principle of bionanotechnology. The availability of these biomodified carbon nanotube constructs opens up an entire new and exciting research direction in the field of chemical biology, finally aiming to target and to alter the cell's behaviour at the subcellular or molecular level. This review covers the latest advances of bio-functionalized carbon nanotubes with an emphasis on the development of functional biological nano-interfaces. Topics that are discussed herewith include methods for biomodification of carbon nanotubes, the development of hybrid systems of carbon nanotubes and biomolecules for bioelectronics, and carbon nanotubes as transporters for a specific delivery of peptides and/or genetic material to cells. All of these current research topics aim at translating these biotechnology modified nanotubes into potential novel therapeutic approaches.
Language eng
DOI 10.1088/0957-4484/18/41/412001
Field of Research 100703 Nanobiotechnology
Socio Economic Objective 970103 Expanding Knowledge in the Chemical Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2007, IOP Publishing
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