Setting the stage : from prodrome to treatment resistance in bipolar disorder

Berk, Michael, Conus, Philippe, Lucas, Nellie, Hallam, Karen, Malhi, Gin S., Dodd, Seetal, Yatham, Lakshmi, Yung, Alison and McGorry, Pat 2007, Setting the stage : from prodrome to treatment resistance in bipolar disorder, Bipolar disorders, vol. 9, no. 7, pp. 671-678, doi: 10.1111/j.1399-5618.2007.00484.x.

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Title Setting the stage : from prodrome to treatment resistance in bipolar disorder
Author(s) Berk, MichaelORCID iD for Berk, Michael
Conus, Philippe
Lucas, Nellie
Hallam, Karen
Malhi, Gin S.
Dodd, SeetalORCID iD for Dodd, Seetal
Yatham, Lakshmi
Yung, Alison
McGorry, Pat
Journal name Bipolar disorders
Volume number 9
Issue number 7
Start page 671
End page 678
Publisher Wiley-Blackwell Munksgaard
Place of publication Copenhagen, Denmark
Publication date 2007-11
ISSN 1398-5647
Summary Bipolar disorder is common, and both difficult to detect and diagnose. Treatment is contingent on clinical needs, which differ according to phase and stage of the illness. A staging model could allow examination of the longitudinal course of the illness and the temporal impact of interventions and events. It could allow for a structured examination of the illness, which could set the stage for algorithms that are tailored to the individuals needs. A staging model could further provide as structure for assessment, gauging treatment and outcomes. The model incorporates prodromal stages and emphasizes early detection and algorithm appropriate intervention where possible. At the other end of the spectrum, the model attempts to operationalize treatment resistance. The utility of the model will need to be validated by empirical research.
Notes First published online 2 November, 2007
DOI 10.1111/j.1399-5618.2007.00484.x
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2007, Blackwell Munksgaard
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School of Medicine
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