Monitoring the safe use of Clozapine : a consensus view from Victoria, Australia

Berk, Michael, Fitzsimons, Joanna, Lambert, Timothy, Pantelis, Christos, Kulkarni, Jayashri, Castle, David, Ryan, Elizabeth W, Jespersen, Sean, McGorry, Pat, Berger, Gregor, Kuluris, Bill, Callaly, Tom and Dodd, Seetal 2007, Monitoring the safe use of Clozapine : a consensus view from Victoria, Australia, CNS drugs, vol. 21, no. 2, pp. 117-127.

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Title Monitoring the safe use of Clozapine : a consensus view from Victoria, Australia
Author(s) Berk, MichaelORCID iD for Berk, Michael
Fitzsimons, Joanna
Lambert, Timothy
Pantelis, Christos
Kulkarni, Jayashri
Castle, David
Ryan, Elizabeth W
Jespersen, Sean
McGorry, Pat
Berger, Gregor
Kuluris, Bill
Callaly, Tom
Dodd, SeetalORCID iD for Dodd, Seetal
Journal name CNS drugs
Volume number 21
Issue number 2
Start page 117
End page 127
Publisher ADIS International
Place of publication London, England
Publication date 2007
ISSN 1172-7047
Summary Clozapine is an important antipsychotic agent that has a unique profile of clinical benefits, but that has also been associated with several serious and potentially life-threatening safety concerns. In order to minimise the impact of haematological adverse events, health professionals treating patients with clozapine are currently required to register their patients on a centrally administered data network and to conform to strict protocols. The consensus statement documented in this article extends existing protocols by recommending monitoring of patients treated with clozapine for additional adverse effects during treatment. This consensus statement reflects the current practice at five major public psychiatric hospitals in Victoria, Australia, for the monitoring and management of clozapine-related adverse events, and has been implemented at these sites because of emerging safety concerns associating clozapine with cardiovascular and metabolic adverse effects.
Language eng
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2007, ADIS International
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School of Medicine
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