Health-related quality of life and functioning in bipolar disorder : the impact of pharmacotherapy Berk, Michael, Hallam, Karen, Lucas, Nellie, Kader, Linda, MacNeil, Craig, Hasty, Melissa, Dodd, Seetal, Malhi, Gin and Conus, Philippe 2006, Health-related quality of life and functioning in bipolar disorder : the impact of pharmacotherapy, Expert review of pharmacoeconomics and outcomes research, vol. 6, no. 5, pp. 509-523. Attached Files Name Description MIMEType Size Downloads dodd-healthrelated-2006.pdf Published version application/pdf 3.40MB 176 Title Health-related quality of life and functioning in bipolar disorder : the impact of pharmacotherapy Author(s) Berk, Michael orcid.org/0000-0002-5554-6946 Hallam, Karen Lucas, Nellie Kader, Linda MacNeil, Craig Hasty, Melissa Dodd, Seetal orcid.org/0000-0002-7918-4636 Malhi, Gin Conus, Philippe Journal name Expert review of pharmacoeconomics and outcomes research Volume number 6 Issue number 5 Start page 509 End page 523 Publisher Expert Reviews Place of publication London, England Publication date 2006-10 ISSN 1473-7167 1744-8379 Keyword(s) atypical antipsychotic rating scale quetiapine mania health-related quality of life depression bipolar disorder Summary Bipolar disorder has a major deleterious impact on many aspects of a patient's functioning and health-related quality of life. Although the formal measurement of these deficits has been neglected until recently, many well-designed trials now include an assessment of functioning and health-related quality of life using one or more rating scales. This review describes recent developments in the measurement of functioning and health-related quality of life in bipolar disorder, and discusses the evidence that medications that improve symptoms in bipolar disorder also offer clinically relevant benefits in functioning and health-related quality of life. Direct comparisons of the benefits of medications including atypical antipsychotics are problematic due to differences in trial populations, study durations and rating scales. Data from quetiapine trials indicate that this medication offers prompt and sustained improvement of functioning in patients with mania and enhancement of health-related quality of life in patients with bipolar depression, to accompany the significant improvements in mood episodes. Notes Reproduced with the kind permission of the copyright owner. Language eng Field of Research 119999 Medical and Health Sciences not elsewhere classified Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category C1.1 Refereed article in a scholarly journal Copyright notice ©2006, Expert Reviews Free to Read? Yes Persistent URL http://hdl.handle.net/10536/DRO/DU:30035550 Document type: Journal Article Collections: Faculty of Health School of Medicine Open Access Collection Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Wed, 22 Jun 2011, 12:34:12 EST Fri, 07 Oct 2011, 12:40:51 EST Fri, 07 Oct 2011, 12:46:41 EST Fri, 07 Oct 2011, 12:49:02 EST Tue, 11 Oct 2011, 12:43:22 EST Thu, 22 Mar 2012, 10:29:33 EST Fri, 23 Mar 2012, 10:25:09 EST Mon, 16 Jun 2014, 18:22:50 EST Tue, 05 Dec 2017, 10:51:25 EST Fri, 07 Sep 2018, 15:28:04 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 2 times in Scopus Search Google Scholar Access Statistics: 806 Abstract Views, 178 File Downloads  -  Detailed Statistics Created: Wed, 22 Jun 2011, 12:34:11 EST