The safety of medications for the treatment of bipolar disorder during pregnancy and the peurperium Dodd, S. and Berk, M. 2006, The safety of medications for the treatment of bipolar disorder during pregnancy and the peurperium, Current drug safety, vol. 1, no. 1, pp. 25-33. Attached Files Name Description MIMEType Size Downloads Title The safety of medications for the treatment of bipolar disorder during pregnancy and the peurperium Author(s) Dodd, S. orcid.org/0000-0002-7918-4636 Berk, M. orcid.org/0000-0002-5554-6946 Journal name Current drug safety Volume number 1 Issue number 1 Start page 25 End page 33 Publisher Bentham Science Publishers Place of publication Bussum, The Netherlands Publication date 2006-01 ISSN 1574-8863 2212-3911 Summary Risks associated with pharmacological treatment of bipolar disorder are heightened during reproductive events. Treatments need to be planned with the mutual agreement of both the treating physician and the patient and tailored to the needs of the individual so as to minimise risk while providing adequate treatment. Conventional treatments have all been associated with teratogeny in first trimester exposure, lithium with cardiac malformation and valproate and carbamazepine with neural tube malformations. There have been an insufficient number of first trimester exposures to the newer anticonvulsant mood stabilisers, lamotrigine and oxcarbazepine, to determine whether there is a safety advantage in switching to these agents. Increasingly, atypical antipsychotics are being suggested as useful agents for the treatment of bipolar disorder. While not known to be teratogenic, there are other reproductive safety concerns associated with these agents. Bipolar disorder patients may be prescribed antidepressants, and many of these agents are associated with a low safety risk during reproductive events, however data regarding use of these agents are currently equivocal. Adverse outcomes from inadequate pharmacological prophylaxis have been documented for both the mother and the baby. Risks and benefits need to be carefully balanced based on an accurate review of the evidence. Language eng Field of Research 110319 Psychiatry (incl Psychotherapy) Socio Economic Objective 920410 Mental Health HERDC Research category C1.1 Refereed article in a scholarly journal Copyright notice ©2006, Bentham Science Publishers Persistent URL http://hdl.handle.net/10536/DRO/DU:30035584 Document type: Journal Article Collections: Faculty of Health School of Medicine Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Wed, 22 Jun 2011, 12:37:00 EST Mon, 10 Oct 2011, 10:29:51 EST Mon, 10 Oct 2011, 10:32:44 EST Tue, 11 Oct 2011, 13:52:59 EST Fri, 19 Jul 2013, 09:50:32 EST Mon, 16 Jun 2014, 18:24:11 EST Filtered Full Citation counts:   Cited 11 times in TR Web of Science Cited 16 times in Scopus Search Google Scholar Access Statistics: 645 Abstract Views, 0 File Downloads  -  Detailed Statistics Created: Wed, 22 Jun 2011, 12:37:00 EST