DIOXOLANE NORBORNANE / NORBORNENE COMPOUNDS SUITABLE AS ANTIMICROBIAL AGENTS TO TREAT BACTERIAL INFECTIONS Pfeffer, Frederick, Henderson, Luke, Li, Jian and Nation, Roger 2010, DIOXOLANE NORBORNANE / NORBORNENE COMPOUNDS SUITABLE AS ANTIMICROBIAL AGENTS TO TREAT BACTERIAL INFECTIONS, Other international (5) Patent WO 2010099573 (A1). Attached Files Name Description MIMEType Size Downloads Title DIOXOLANE NORBORNANE / NORBORNENE COMPOUNDS SUITABLE AS ANTIMICROBIAL AGENTS TO TREAT BACTERIAL INFECTIONS Creator(s) Pfeffer, Frederick orcid.org/0000-0002-5441-6437 Henderson, Luke orcid.org/0000-0002-4244-2056 Li, Jian Nation, Roger Date 2010-09-10 Patent no. WO 2010099573 (A1) Patent owner UNIV DEAKIN, Frederick Pfeffer, Luke Henderson, Jian Li, Roger Nation Registry Office Other international (5) Patent family name DIOXOLANE NORBORNANE / NORBORNENE COMPOUNDS SUITABLE AS ANTIMICROBIAL AGENTS TO TREAT BACTERIAL INFECTIONS Summary The invention provides a compound including : A core having a first face and a second face; A binding portion attached to the first face of the core, wherein the binding portion is capable of binding to an anionic group present in a cell membrane of a microorganism; and A hydrophobic portion attached to the second face of the core, wherein the hydrophobic portion is capable of interacting with the cell membrane of the microorganism; and The core comprises a dioxolane norbornane / norbornene of formula (II): Or a salt or ion thereof, wherein R' is a moiety forming part of a hydrophobic portion; R2 is a first binding portion; and R3 is a seconding binding portion. The invention also provides compositions including at least one such compound. The invention also provides methods and uses for treatment or prophylaxis of infection of a mammal by a microorganism, and methods and uses for treating or preventing contamination of a substrate by a microorganism, using the compounds and compositions. Language eng Field of Research 060501 Bacteriology 060599 Microbiology not elsewhere classified HERDC Research category I Patents ERA Research output type I Patents Copyright notice ©2010, Deakin University, Frederick Pfeffer, Luke Henderson, Jian Li, Roger Nation Persistent URL http://hdl.handle.net/10536/DRO/DU:30036020 Document type: Patent Collections: Faculty of Science, Engineering and Built Environment School of Life and Environmental Sciences Related Links Link Description Connect to published description Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Tue, 26 Jul 2011, 16:31:14 EST Wed, 04 Jan 2012, 12:54:09 EST Fri, 17 Oct 2014, 11:00:21 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 0 times in Scopus Search Google Scholar Access Statistics: 340 Abstract Views, 0 File Downloads  -  Detailed Statistics Created: Tue, 26 Jul 2011, 16:31:07 EST by Lesa Maclean