Effects of variation in modulator temperature during cryogenic modulation in comprehensive two-dimensional gas chromatography Begnaud, Frédéric, Debonneville, Christian, Probst, Jean-Pierre, Chaintreau, Alain, Morrison, Paul D., Adcock, Jacqui L. and Marriott, Philip J. 2009, Effects of variation in modulator temperature during cryogenic modulation in comprehensive two-dimensional gas chromatography, Journal of separation science, vol. 32, no. 18, pp. 3144-3151, doi: 10.1002/jssc.200900290. Attached Files Name Description MIMEType Size Downloads Title Effects of variation in modulator temperature during cryogenic modulation in comprehensive two-dimensional gas chromatography Author(s) Begnaud, Frédéric Debonneville, Christian Probst, Jean-Pierre Chaintreau, Alain Morrison, Paul D. Adcock, Jacqui L. orcid.org/0000-0002-4446-518X Marriott, Philip J. Journal name Journal of separation science Volume number 32 Issue number 18 Start page 3144 End page 3151 Total pages 8 Publisher Wiley - V C H Verlag GmbH & Co. KGaA Place of publication Weinheim, Germany Publication date 2009-09 ISSN 1615-9306 1615-9314 Summary Many modulation systems in comprehensive 2D GC (GC×GC) are based on cryogenic methods. High trapping temperatures in these systems can result in ineffective trapping of the more volatile compounds, whilst temperatures that are too low can prevent efficient remobilisation of some compounds. To better understand the trapping and release of compounds over a wide range of volatilities, we have investigated a number of different constant temperature modulator settings, and have also examined a constant temperature differential between the cryo-trap and the chromatographic oven. These investigations have led us to modify the temperature regulation capabilities of the longitudinally modulated cryogenic system (LMCS). In contrast to the current system, where the user sets a constant temperature for the cooling chamber, the user now sets the temperature difference between the cryo-trap and the chromatographic oven. In this configuration, the cooling chamber temperature increases during the chromatographic run, tracking the oven temperature ramp. This produces more efficient, volatility-dependent modulation, and increases the range of volatile compounds that can be analysed under optimal trap-and-release conditions within a single analytical run. This system also reduces cryogenic fluid consumption. Language eng DOI 10.1002/jssc.200900290 Field of Research 039999 Chemical Sciences not elsewhere classified Socio Economic Objective 970103 Expanding Knowledge in the Chemical Sciences HERDC Research category C1.1 Refereed article in a scholarly journal Copyright notice ©2009 WILEY-VCH Verlag GmbH & Co. KGaA Persistent URL http://hdl.handle.net/10536/DRO/DU:30039134 Document type: Journal Article Collections: Centre for Material and Fibre Innovation GTP Research Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Mon, 24 Oct 2011, 10:53:45 EST Wed, 26 Oct 2011, 08:42:18 EST Wed, 26 Oct 2011, 08:47:33 EST Wed, 26 Oct 2011, 08:48:32 EST Wed, 26 Oct 2011, 08:53:40 EST Wed, 26 Oct 2011, 08:54:43 EST Wed, 02 Nov 2011, 08:02:28 EST Fri, 25 Nov 2011, 09:16:19 EST Thu, 29 Nov 2012, 12:51:43 EST Wed, 12 Jun 2013, 12:42:50 EST Tue, 03 Sep 2013, 11:29:32 EST Fri, 17 Oct 2014, 11:03:40 EST Thu, 11 Dec 2014, 17:22:07 EST Filtered Full Citation counts:   Cited 12 times in TR Web of Science Cited 11 times in Scopus Search Google Scholar Access Statistics: 710 Abstract Views, 5 File Downloads  -  Detailed Statistics Created: Mon, 24 Oct 2011, 10:53:45 EST