Lifestyle factors fail to explain the variation in plasma leptin concentrations in women

de Silva, Andrea, de Courten, Maximilian, Zimmet, Paul, Nicholson, Geoff, Kotowicz, Mark, Pasco, Julie and Collier, Greg R. 1998, Lifestyle factors fail to explain the variation in plasma leptin concentrations in women, Nutrition, vol. 14, no. 9, pp. 653-657, doi: 10.1016/S0899-9007(98)00065-3.

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Title Lifestyle factors fail to explain the variation in plasma leptin concentrations in women
Author(s) de Silva, Andrea
de Courten, Maximilian
Zimmet, Paul
Nicholson, Geoff
Kotowicz, MarkORCID iD for Kotowicz, Mark
Pasco, JulieORCID iD for Pasco, Julie
Collier, Greg R.
Journal name Nutrition
Volume number 14
Issue number 9
Start page 653
End page 657
Total pages 5
Publisher Elsevier
Place of publication London, England
Publication date 1998-09
ISSN 0899-9007
Keyword(s) leptin
lifestyle factors
Summary To assess the relationship between circulating leptin concentrations, metabolic parameters, and lifestyle factors such as alcohol intake, physical activity level, smoking habits, and reproductive history, a cohort of 359 women was drawn from a population-based study conducted in Victoria, Australia. The parameters measured included body mass index (BMI); waist and hip circumference; blood pressure; and fasting glucose, insulin, triacylglycerol, cholesterol, and leptin concentrations. In addition, a self-administered questionnaire was used to assess reproductive history, physical activity level, alcohol intake, and smoking habits. Our results demonstrated that BMI, body weight, waist circumference, and hip circumference were all strongly correlated with circulating leptin concentrations in this population (r > 0.56, P < 0.001 in all cases). Waist/hip ratio, triacylglycerols, insulin, glucose, and cholesterol were also associated with leptin (P < 0.05), but there was no association between leptin and age, height, or blood pressure. When these associations were adjusted for BMI, age, glucose, and waist circumference were significantly associated with leptin. The lifestyle factors examined did not help to explain the observed variation in leptin concentrations between individuals when results were adjusted for degree of adiposity and age.
Language eng
DOI 10.1016/S0899-9007(98)00065-3
Field of Research 119999 Medical and Health Sciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©1998, Elsevier Science
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Document type: Journal Article
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