Catecholamine and oxytocin cells respond to hypovolaemia as well as hypotension

Smith, Doug W. and Day, Trevor A. 2003, Catecholamine and oxytocin cells respond to hypovolaemia as well as hypotension, Neuroreport, vol. 14, no. 11, pp. 1493-1495.

Attached Files
Name Description MIMEType Size Downloads

Title Catecholamine and oxytocin cells respond to hypovolaemia as well as hypotension
Author(s) Smith, Doug W.
Day, Trevor A.
Journal name Neuroreport
Volume number 14
Issue number 11
Start page 1493
End page 1495
Total pages 3
Publisher Lippincott William & Wilkins
Place of publication London, England
Publication date 2003-08-06
ISSN 0959-4965
Keyword(s) catecholamine cells
nucleus of the solitary tract
paraventricular nucleus
supraoptic nucleus
Summary Medullary catecholamine and hypothalamic neurosecretory oxytocin cells are activated by hypotension, but previous studies have provided uncertain outcomes concerning their ability to respond to a purely hypovolaemic stimulus. In the present study, injections of PEG/water and pentolinium were used to elicit non-hypotensive, isosmotic hypovolaemia and isovolaemic, isosmotic hypotension, respectively, in conscious rats. Animals were sacrificed 2 h after treatment. Immunolabelling for Fos, tyrosine hydroxylase and oxytocin established that these two stimuli activate almost identical populations of catecholamine neurons in the ventrolateral and dorsomedial medulla, and very similar populations of oxytocin cells in the supraoptic and paraventricular nuclei of the hypothalamus.
Language eng
Field of Research 060199 Biochemistry and Cell Biology not elsewhere classified
Socio Economic Objective 970106 Expanding Knowledge in the Biological Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2003, Lippincott Williams & Wilkins
Persistent URL

Document type: Journal Article
Collection: Faculty of Science, Engineering and Built Environment
Connect to link resolver
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 0 times in TR Web of Science
Scopus Citation Count Cited 13 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 496 Abstract Views, 0 File Downloads  -  Detailed Statistics
Created: Thu, 19 Apr 2012, 10:26:21 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact