Direct methods for distinction between endogenous and exogenous erythropoietin Lamon, Séverine, Robinson, Neil and Saugy, Martial 2011, Direct methods for distinction between endogenous and exogenous erythropoietin. In Ghigo, Ezio, Lanfranco, Fabio and Strasburger, Christian J. (ed), Hormone use and abuse by athletes, Springer, New York, N. Y., pp.163-175, doi: 10.1007/978-1-4419-7014-5_17. Attached Files Name Description MIMEType Size Downloads Title Direct methods for distinction between endogenous and exogenous erythropoietin Author(s) Lamon, Séverine orcid.org/0000-0002-3271-6551 Robinson, Neil Saugy, Martial Title of book Hormone use and abuse by athletes Editor(s) Ghigo, Ezio Lanfranco, Fabio Strasburger, Christian J. Publication date 2011 Series Endocrine updates Chapter number 17 Total chapters 17 Start page 163 End page 175 Total pages 13 Publisher Springer Place of Publication New York, N. Y. Keyword(s) anti-doping athletes artificial performance enhancer hemoglobin blood doping rhEPO Summary Since the commercialization of the first recombinant human erythropoietin (rhEPO) product (epoetin-a) in 1989 as a treatment for acute anemia, rhEPO detection has represented a continuous challenge for the anti-doping fight. Indeed, it appeared rapidly that this ergogenic hormone would be abused by athletes looking for an artificial performance enhancer. Hemoglobin is one of the principal modulators of aerobic power [1, 2] and, consequently, of performance in endurance sports [3]. By stimulating the red blood cells production, EPO is known to raise hemoglobin concentration in a dose-dependant and predictable way. Therefore, this hormone soon became one of the athletes most popular doping agent. Since 1984, all forms of blood doping in sport have been officially banned. In 1990, the IOC medical commission, which was in charge of the anti-doping regulations, added rhEPO to the list of the prohibited drugs in sports, even if a direct test allowing to detect the molecule became available a decade after only. ISBN 1441970134 9781441970138 Language eng DOI 10.1007/978-1-4419-7014-5_17 Field of Research 119999 Medical and Health Sciences not elsewhere classified Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category B1.1 Book chapter Copyright notice ©2011, Springer Science+Business Media, LLC Persistent URL http://hdl.handle.net/10536/DRO/DU:30045280 Document type: Book Chapter Collections: Faculty of Health School of Exercise and Nutrition Sciences Institute for Physical Activity and Nutrition Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Mon, 14 May 2012, 15:07:24 EST Tue, 15 May 2012, 12:17:00 EST Tue, 15 May 2012, 12:19:00 EST Thu, 07 Aug 2014, 09:12:18 EST Filtered Full Citation counts:   Cited 1 times in TR Web of Science Cited 0 times in Scopus Search Google Scholar Access Statistics: 542 Abstract Views, 4 File Downloads  -  Detailed Statistics Created: Mon, 14 May 2012, 15:07:24 EST

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