The population cost-effectiveness of interventions designed to prevent childhood depression

Mihalopoulos, Catherine, Vos, Theo, Pirkis, Jane and Carter, Rob 2012, The population cost-effectiveness of interventions designed to prevent childhood depression, Pediatrics, vol. 129, no. 3, pp. 723-730, doi: 10.1542/peds.2011-1823.

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Title The population cost-effectiveness of interventions designed to prevent childhood depression
Author(s) Mihalopoulos, CatherineORCID iD for Mihalopoulos, Catherine
Vos, Theo
Pirkis, Jane
Carter, RobORCID iD for Carter, Rob
Journal name Pediatrics
Volume number 129
Issue number 3
Start page 723
End page 730
Total pages 8
Publisher American Academy of Pediatrics
Place of publication Elk Grove Village, Ill.
Publication date 2012-03-01
ISSN 0031-4005
Keyword(s) childhood depression
economic evaluation
Summary BACKGROUND AND OBJECTIVES: Depression in childhood and adolescence is common and often persists into adulthood. This study assessed the population-level cost-effectiveness of a preventive intervention that screens children and adolescents for symptoms of depression in schools and the subsequent provision of a psychological intervention to those showing elevated signs of depression. The target population for screening comprised 11- to 17-year-old children and adolescents in the 2003 Australian population.

METHODS: Economic modeling techniques were used to assess the incremental cost-effectiveness of the intervention compared with no intervention. The perspective was that of the health sector, and outcomes were measured by using disability-adjusted life-years (DALYs). Multivariate probabilistic and univariate sensitivity testing was applied to quantify variations in the model parameters.

The modeled psychological intervention had an incremental cost-effectiveness ratio of $5400 per DALY averted, with just 2% of iterations falling above a $50 000 per DALY value-for-money threshold. Results were robust to model assumptions.

After school screening, screening and the psychological intervention represent good value-for-money. Such an intervention needs to be seriously considered in any national package of preventive health services. Acceptability issues, particularly to intervention providers, including schools and mental health professionals, need to be considered before wide-scale adoption.
Language eng
DOI 10.1542/peds.2011-1823
Field of Research 140208 Health Economics
Socio Economic Objective 920207 Health Policy Economic Outcomes
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2012, American Academy of Pediatrics
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Document type: Journal Article
Collections: Faculty of Health
Population Health
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Created: Mon, 11 Jun 2012, 10:53:11 EST by Jane Moschetti

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