A comparison of two methods in acquiring stimulus-response curves with transcranial magnetic stimulation Pearce, Alan J., Clark, Ross A. and Kidgell, Dawson J. 2012, A comparison of two methods in acquiring stimulus-response curves with transcranial magnetic stimulation, Brain stimulation, vol. 6, no. 3, pp. 306-309, doi: 10.1016/j.brs.2012.05.010. Attached Files Name Description MIMEType Size Downloads Title A comparison of two methods in acquiring stimulus-response curves with transcranial magnetic stimulation Author(s) Pearce, Alan J. Clark, Ross A. Kidgell, Dawson J. Journal name Brain stimulation Volume number 6 Issue number 3 Start page 306 End page 309 Total pages 4 Publisher Elsevier Inc. Place of publication Philadelphia, Pa. Publication date 2012-05 ISSN 1935-861X Keyword(s) transcranial magnetic stimulation arm hand stimulus–response curve Summary Background The stimulus–response (S–R) curve is a well accepted constituent in transcranial magnetic stimulation (TMS) studies. However, it has been suggested that parameters of the S–R curve differ when stimuli are provided in a “ramped” (measured steps from low to high intensity), or “random” fashion. Hypothesis We hypothesized that there would be no difference in the parameters of the S–R curve between either methodologies. Methods Using a randomised cross-over design, 10 healthy participants (29.6 ± 6.4 yrs, 3 f) completed “ramped” or “random” curves in biceps brachii (BB) and first dorsal interosseous (FDI) muscles of both limbs. Curves were compared using mixed-factor ANOVA and correlated between limbs and methodologies. Results No differences (P > 0.05) and high correlations (range 0.71–0.97; P < 0.001) were observed in BB and FDI data between curves. Conclusions This study demonstrated that either methodology provides similar parameters of the S–R curve in healthy participants. Language eng DOI 10.1016/j.brs.2012.05.010 Field of Research 110903 Central Nervous System Socio Economic Objective 920412 Preventive Medicine HERDC Research category C1 Refereed article in a scholarly journal Persistent URL http://hdl.handle.net/10536/DRO/DU:30046042 Document type: Journal Article Collections: Faculty of Health School of Psychology Institute for Physical Activity and Nutrition Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Tue, 03 Jul 2012, 11:30:25 EST Thu, 05 Jul 2012, 14:09:02 EST Thu, 05 Jul 2012, 14:10:09 EST Thu, 06 Dec 2012, 13:39:45 EST Thu, 11 Apr 2013, 14:11:12 EST Tue, 28 May 2013, 15:23:46 EST Tue, 28 May 2013, 15:32:47 EST Tue, 28 May 2013, 15:33:35 EST Mon, 17 Jun 2013, 17:44:10 EST Fri, 17 Oct 2014, 11:34:44 EST Filtered Full Citation counts:   Cited 26 times in TR Web of Science Cited 23 times in Scopus Search Google Scholar Access Statistics: 419 Abstract Views, 2 File Downloads  -  Detailed Statistics Created: Tue, 03 Jul 2012, 11:30:12 EST by Jane Moschetti