Dietary intake of fish and PUFA, and clinical depressive and anxiety disorders in women Jacka, Felice N., Pasco, Julie A., Williams, Lana J., Meyer, Barbara J., Digger, Rebecca and Berk, Michael 2013, Dietary intake of fish and PUFA, and clinical depressive and anxiety disorders in women, British journal of nutrition, vol. 109, no. 11, pp. 2059-2066, doi: 10.1017/S0007114512004102. Attached Files Name Description MIMEType Size Downloads jacka-dietaryintake-2012.pdf Published version application/pdf 131.81KB 357 Title Dietary intake of fish and PUFA, and clinical depressive and anxiety disorders in women Author(s) Jacka, Felice N. orcid.org/0000-0002-9825-0328 Pasco, Julie A. orcid.org/0000-0002-8968-4714 Williams, Lana J. orcid.org/0000-0002-1377-1272 Meyer, Barbara J. Digger, Rebecca Berk, Michael orcid.org/0000-0002-5554-6946 Journal name British journal of nutrition Volume number 109 Issue number 11 Start page 2059 End page 2066 Total pages 8 Publisher Cambridge University Press Place of publication Cambridge, England Publication date 2013-06 ISSN 0007-1145 1475-2662 Keyword(s) n-3 n-6 PUFA depression anxiety diet nutrition Summary Fish and PUFA consumption are thought to play a role in mental health; however, many studies do not take into account multiple sources of PUFA. The present study analysed data from a sample of 935 randomly selected, population-based women aged 20–93 years. A validated and comprehensive dietary questionnaire ascertained the consumption of n-3 and n-6 PUFA. Another assessed fish and energy intake and provided data for a dietary quality score. The General Health Questionnaire-12 (GHQ-12) measured psychological symptoms and a clinical interview (Structured Clinical Interview for DSM-IV-TR Research Version, Non-patient edition) assessed depressive and anxiety disorders. Median dietary intakes of long-chain n-3 fatty acids (310 mg/d) were below suggested dietary target levels. The only PUFA related to categorical depressive and anxiety disorders was DHA. There was a non-linear relationship between DHA intake and depression; those in the second tertile of DHA intake were nearly 70 % less likely to report a current depressive disorder compared to those in the first tertile. The relationship of DHA to anxiety disorders was linear; for those in the highest tertile of DHA intake, the odds for anxiety disorders were reduced by nearly 50 % after adjustments, including adjustment for diet quality scores, compared to the lowest tertile. Those who ate fish less than once per week had higher GHQ-12 scores, and this relationship was particularly obvious in smokers. These are the first observational data to indicate a role for DHA in anxiety disorders, but suggest that the relationship between DHA and depressive disorders may be non-linear. Language eng DOI 10.1017/S0007114512004102 Field of Research 119999 Medical and Health Sciences not elsewhere classified Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category C1 Refereed article in a scholarly journal Grant ID NHMRC 628912 Copyright notice ©2012, The Authors Free to Read? Yes Persistent URL http://hdl.handle.net/10536/DRO/DU:30047612 Document type: Journal Article Collections: Faculty of Health School of Medicine Open Access Collection Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Thu, 30 Aug 2012, 09:48:31 EST Thu, 30 Aug 2012, 10:41:25 EST Thu, 25 Oct 2012, 12:30:30 EST Thu, 25 Oct 2012, 12:33:57 EST Wed, 23 Jan 2013, 14:24:54 EST Wed, 17 Apr 2013, 14:21:32 EST Mon, 15 Jul 2013, 13:36:24 EST Tue, 16 Jul 2013, 09:06:15 EST Tue, 16 Jul 2013, 09:13:22 EST Tue, 16 Jul 2013, 09:19:51 EST Tue, 16 Jul 2013, 09:23:26 EST Mon, 10 Feb 2014, 16:04:36 EST Mon, 12 May 2014, 15:22:49 EST Fri, 13 Jun 2014, 15:13:23 EST Tue, 05 Dec 2017, 12:35:27 EST Fri, 07 Sep 2018, 16:08:29 EST Filtered Full Citation counts:   Cited 54 times in TR Web of Science Cited 64 times in Scopus Search Google Scholar Access Statistics: 1339 Abstract Views, 357 File Downloads  -  Detailed Statistics Created: Thu, 30 Aug 2012, 09:48:31 EST