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Zinc and docosahexaenoic acid metabolism in brain cells

Sadli, Nadia Christella 2012, Zinc and docosahexaenoic acid metabolism in brain cells, Ph.D thesis, School of Life and Environmental Sciences, Deakin University.

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Title Zinc and docosahexaenoic acid metabolism in brain cells
Author Sadli, Nadia Christella
Institution Deakin University
School School of Life and Environmental Sciences
Faculty Faculty of Science and Technology
Degree type Research doctorate
Degree name Ph.D
Thesis advisor Suphioglu, CenkORCID iD for Suphioglu, Cenk orcid.org/0000-0003-0101-0668
Date submitted 2012-05
Summary This thesis examines the direct interaction of Docosahexaenoic acid (DHA, an omega-3 fatty acid) against zinc-induced mitochondrial dysfunction and involvement of bioenergetic regulation as a zinc toxicity target, which may be the initiator of oxidative stress, caspase cascade, alteration in epigenetic patterns and therefore gene expression in human neuronal cells.
Language eng
Socio Economic Objective 920112 Neurodegenerative Disorders Related to Ageing
Description of original 173 p.
Copyright notice ©The author
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30048924

Document type: Thesis
Collections: Higher degree theses (Open Access)
Open Access Collection
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Created: Mon, 08 Oct 2012, 15:37:33 EST by Belinda Lee

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.