Does the longer application of anodal-transcranial direct current stimulaton increase corticomotor excitability further? A pilot study Jaberzadeh, Shapour, Bastani, Andisheh and Kidgell, Dawson 2012, Does the longer application of anodal-transcranial direct current stimulaton increase corticomotor excitability further? A pilot study, Basic and clinical neuroscience, vol. 3, no. 4, pp. 28-35. Attached Files Name Description MIMEType Size Downloads kidgell-doesthelonger-2012.pdf Published version application/pdf 1.22MB 73 Title Does the longer application of anodal-transcranial direct current stimulaton increase corticomotor excitability further? A pilot study Author(s) Jaberzadeh, Shapour Bastani, Andisheh Kidgell, Dawson Journal name Basic and clinical neuroscience Volume number 3 Issue number 4 Start page 28 End page 35 Total pages 8 Publisher Tehran University of Medical Sciences Place of publication Tehran, Iran Publication date 2012 ISSN 2228-7442 2008-126X Keyword(s) transcranial direct current stimulation (tDCS) transcranial magnetic stimulation (TMS) corticomotor excitability Summary Introduction: Anodal transcranial direct current stimulation (a-tDCS) of the primary motor cortex (M1) has been shown to be effective in increasing corticomotor excitability. 　 Methods: We investigated whether longer applications of a-tDCS coincide with greater increases in corticomotor excitability compared to shorter application of a-tDCS. Ten right-handed healthy participants received one session of a-tDCS (1mA current) with shorter (10 min) and longer (10+10 min) stimulation durations applied to the left M1 of extensor carpi radialis muscle (ECR). Corticomotor excitability following application of a-tDCS was assessed at rest with transcranial magnetic stimulation (TMS) elicited motor evoked potentials (MEP) and compared with baseline data for each participant. 　 Results: MEP amplitudes were increased following 10 min of a-tDCS by 67% (p = 0.001) with a further increase (32%) after the second 10 min of a-tDCS (p = 0.005). MEP amplitudes remained elevated at 15 min post stimulation compared to baseline values by 65% (p = 0.02). 　 Discussion: The results demonstrate that longer application of a-tDCS within the recommended safety limits, increases corticomotor excitability with after effects of up to 15 minutes post stimulation. Language eng Field of Research 110903 Central Nervous System Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category C1.1 Refereed article in a scholarly journal Copyright notice ©2012, Tehran University of Medical Sciences Free to Read? Yes Persistent URL http://hdl.handle.net/10536/DRO/DU:30052593 Document type: Journal Article Collections: Faculty of Health Institute for Physical Activity and Nutrition Open Access Collection Related Links Link Description Connect to published version Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Thu, 23 May 2013, 14:45:45 EST Fri, 24 May 2013, 08:44:21 EST Mon, 27 May 2013, 14:20:17 EST Mon, 27 May 2013, 14:22:53 EST Mon, 27 May 2013, 14:23:38 EST Thu, 30 May 2013, 14:30:31 EST Fri, 13 Jun 2014, 17:23:24 EST Fri, 17 Oct 2014, 12:06:12 EST Wed, 11 Mar 2015, 14:06:49 EST Wed, 11 Mar 2015, 14:41:06 EST Fri, 09 Oct 2015, 17:07:15 EST Mon, 12 Oct 2015, 15:17:32 EST Tue, 06 Sep 2016, 21:05:14 EST Tue, 05 Dec 2017, 12:40:43 EST Fri, 07 Sep 2018, 16:30:17 EST Filtered Full Citation counts:   Cited 4 times in TR Web of Science Cited 6 times in Scopus Search Google Scholar Access Statistics: 131 Abstract Views, 74 File Downloads  -  Detailed Statistics Created: Thu, 23 May 2013, 14:45:31 EST by Jane Moschetti