Integrated microfluidic drug delivery devices : a component view

Samad, Mst. Fateha and Kouzani, Abbas Z. 2013, Integrated microfluidic drug delivery devices : a component view, Microsystem technologies, vol. 19, no. 7, pp. 957-970, doi: 10.1007/s00542-013-1770-7.

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Title Integrated microfluidic drug delivery devices : a component view
Author(s) Samad, Mst. Fateha
Kouzani, Abbas Z.ORCID iD for Kouzani, Abbas Z.
Journal name Microsystem technologies
Volume number 19
Issue number 7
Start page 957
End page 970
Total pages 14
Publisher Springer
Place of publication Berlin, Germany
Publication date 2013-07
ISSN 0946-7076
Keyword(s) drug delivery devices
design and fabrication
Summary Research on drug delivery devices is progressing rapidly with the main objective being the delivery of precise quantity of drugs into the target area of the body. A drug delivery device (DDD) needs to accurately control the flow rate of drug delivery and protects the body from undesired additional doses. An integrated microfluidic drug delivery device (IMDDD) is a miniature device that can regulate and monitor the delivery of the right amount of drug using micro-scale components. IMDDDs offer several advantages including ease of use, electro-chemical controllability, low power consumption, simplicity, fast fabrication, and good bio-compatibility. Various IMDDDs have been developed for treatment of cancer, cardiovascular disorder, eye and brain diseases, stress, and diabetes. This paper presents a generic architecture for IMDDDs, discusses the existing drug delivery methods, summarizes the specifications of the components, and identifies a number of performance evaluation parameters. The operation of IMDDDs is presented through fourteen potential internal components. In addition, recommendations on how enhance the design and fabrication process of IMDDDs are given.
Language eng
DOI 10.1007/s00542-013-1770-7
Field of Research 090304 Medical Devices
Socio Economic Objective 861502 Medical Instruments
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2013, Springer
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