Neuroendocrine neoplasms of the GI tract : the role of cytotoxic chemotherapy Khasraw, Mustafa, Yap, Saw Yee and Ananda, Sumitra 2013, Neuroendocrine neoplasms of the GI tract : the role of cytotoxic chemotherapy, Expert review of anticancer therapy, vol. 13, no. 4, pp. 451-459. Attached Files Name Description MIMEType Size Downloads Title Neuroendocrine neoplasms of the GI tract : the role of cytotoxic chemotherapy Author(s) Khasraw, Mustafa orcid.org/0000-0003-3249-9849 Yap, Saw Yee Ananda, Sumitra Journal name Expert review of anticancer therapy Volume number 13 Issue number 4 Start page 451 End page 459 Total pages 9 Publisher Expert Reviews Place of publication London, England Publication date 2013 ISSN 1473-7140 1744-8328 Summary Neuroendocrine neoplasms (NENs) comprise a heterogeneous group of neoplasms derived from peptide- and amine-secreting cells of the neuroendocrine system. NENs commonly arise in the GI tract but can arise in most organs of the body. NENs in different organs share many common pathologic features. Although the incidence of NENs is not high, the prevalence is not low because many patients may live relatively long periods without major symptoms from the disease. While many of these tumors lead an indolent clinical course, they constitute a therapeutic challenge when they progress, metastasize and become symptomatic. Treatment requires a multidisciplinary approach including cytotoxic chemotherapy. Almost all clinical trials investigating cytotoxic chemotherapy in NENs are small single-arm studies and guidelines are derived from expert opinion and from extrapolating results from small cell lung cancer studies. This article briefly reviews NENs before focusing on reviewing data on the role of cytotoxic chemotherapy studies in NENs. Language eng Field of Research 111203 Cancer Genetics Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category C1 Refereed article in a scholarly journal Persistent URL http://hdl.handle.net/10536/DRO/DU:30052790 Document type: Journal Article Collections: Faculty of Health School of Medicine Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Mon, 03 Jun 2013, 13:10:44 EST Tue, 04 Jun 2013, 08:49:53 EST Tue, 04 Jun 2013, 15:42:07 EST Fri, 13 Jun 2014, 17:27:53 EST Thu, 18 Sep 2014, 11:22:17 EST Thu, 18 Sep 2014, 11:23:02 EST Thu, 18 Sep 2014, 11:25:52 EST Filtered Full Citation counts:   Cited 4 times in TR Web of Science Cited 4 times in Scopus Search Google Scholar Access Statistics: 497 Abstract Views, 0 File Downloads  -  Detailed Statistics Created: Mon, 03 Jun 2013, 13:10:32 EST by Jane Moschetti