Gender differences in first episode psychotic mania Cotton, Sue M., Lambert, Martin, Berk, Michael, Schimmelmann, Benno G., Butselaar, Felicity J., McGorry, Patrick D. and Conus, Philippe 2013, Gender differences in first episode psychotic mania, BMC psychiatry, vol. 13, Article 82, pp. 1-8, doi: 10.1186/1471-244X-13-82. Attached Files Name Description MIMEType Size Downloads berk-genderdifferences-2013.pdf Published version application/pdf 174.60KB 283 Title Gender differences in first episode psychotic mania Author(s) Cotton, Sue M. Lambert, Martin Berk, Michael orcid.org/0000-0002-5554-6946 Schimmelmann, Benno G. Butselaar, Felicity J. McGorry, Patrick D. Conus, Philippe Journal name BMC psychiatry Volume number 13 Season Article 82 Start page 1 End page 8 Total pages 8 Publisher BioMed Central Place of publication London, England Publication date 2013 ISSN 1471-244X Keyword(s) gender mania psychosis bipolar disorder Summary Background : The aim of this paper was to delineate the impact of gender on premorbid history, onset, and 18 month outcomes of first episode psychotic mania (FEPM) patients. Methods : Medical file audit assessment of 118 (male = 71; female = 47) patients with FEPM aged 15 to 29 years was undertaken on clinical and functional measures. Results : Males with FEPM had increased likelihood of substance use (OR = 13.41, p < .001) and forensic issues (OR = 4.71, p = .008), whereas females were more likely to have history of sexual abuse trauma (OR = 7.12, p = .001). At service entry, males were more likely to be using substances, especially cannabis (OR = 2.15, p = .047), had more severe illness (OR = 1.72, p = .037), and poorer functioning (OR = 0.96, p = .045). During treatment males were more likely to decrease substance use (OR = 5.34, p = .008) and were more likely to be living with family (OR = 4.30, p = .009). There were no gender differences in age of onset, psychopathology or functioning at discharge. Conclusions : Clinically meaningful gender differences in FEPM were driven by risk factors possibly associated with poor outcome. For males, substance use might be associated with poorer clinical presentation and functioning. In females with FEPM, the impact of sexual trauma on illness course warrants further consideration. Language eng DOI 10.1186/1471-244X-13-82 Field of Research 110999 Neurosciences not elsewhere classified Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category C1 Refereed article in a scholarly journal Copyright notice ©2013, BioMed Central Free to Read? Yes Persistent URL http://hdl.handle.net/10536/DRO/DU:30052825 Document type: Journal Article Collections: Faculty of Health School of Medicine Open Access Collection Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Tue, 04 Jun 2013, 14:23:41 EST Wed, 05 Jun 2013, 09:19:37 EST Fri, 07 Jun 2013, 13:02:49 EST Fri, 07 Jun 2013, 13:04:02 EST Tue, 24 Sep 2013, 10:01:06 EST Tue, 24 Sep 2013, 10:02:48 EST Tue, 06 Sep 2016, 21:08:07 EST Tue, 05 Dec 2017, 12:40:55 EST Fri, 07 Sep 2018, 16:31:46 EST Filtered Full Citation counts:   Cited 13 times in TR Web of Science Cited 12 times in Scopus Search Google Scholar Access Statistics: 1017 Abstract Views, 283 File Downloads  -  Detailed Statistics Created: Tue, 04 Jun 2013, 14:23:30 EST by Jane Moschetti