Using short interfering RNAs to silence individual human host genes we were able to demonstrate that alpha coatamer protein (COPA) is important for the replication of highly pathogenic Avian Influenza A/chicken/Vietnam/008/2004 H5N1 in vitro and may therefore hold potential as a target for novel antiviral therapeutics.
Language
eng
Field of Research
110702 Applied Immunology (incl Antibody Engineering, Xenotransplantation and T-cell Therapies)
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