Estimating nephron number in the developing kidney using the physical disector/fractionator combination Cullen-McEwen, Luise A., Armitage, James A., Nyengaard, Jens R. and Bertram, John F. 2012, Estimating nephron number in the developing kidney using the physical disector/fractionator combination. In Michos, Odysse (ed), Kidney development: methods and protocols, Springer Science & Business Media, Dordrecht, The Netherlands, pp.109-119. Attached Files Name Description MIMEType Size Downloads Title Estimating nephron number in the developing kidney using the physical disector/fractionator combination Author(s) Cullen-McEwen, Luise A. Armitage, James A. orcid.org/0000-0002-3762-0911 Nyengaard, Jens R. Bertram, John F. Title of book Kidney development: methods and protocols Editor(s) Michos, Odysse Publication date 2012 Series Methods in molecular biology 886 Chapter number 10 Total chapters 35 Start page 109 End page 119 Total pages 11 Publisher Springer Science & Business Media Place of Publication Dordrecht, The Netherlands Keyword(s) nephron endowment nephron number kidney development stereology disector metanephros Summary Over the last decade the development of new molecular biology tools, advanced microscopy, live imaging and systems biology approaches have revolutionized our conception of how embryonic development proceeds. One fundamental aspect of development biology is the concept of morphogenesis: understanding how a group of multipotent cells organize and differentiate into a complex organ. In Kidney Development: Methods and Protocols, expert researchers in the field detail different approaches to tackle kidney development. These approaches include culture and live imaging aspects of kidney development, analyzing the 3-dimensional aspects of branching morphogenesis as well as nephrogenesis, manipulation of the gene/protein expression during kidney development as well as in the adult kidney, and how to assess kidney malformation and disease. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Kidney Development: Methods and Protocols seeks to aid scientists in the further study of the process of morphogenesis which is fundamental important not only for studying developmental biology but also for regenerative medicine. ISBN 1617798517 9781617798511 Language eng Field of Research 110312 Nephrology and Urology Socio Economic Objective 920119 Urogenital System and Disorders HERDC Research category B1.1 Book chapter Copyright notice ©2012, Springer Persistent URL http://hdl.handle.net/10536/DRO/DU:30056687 Document type: Book Chapter Collections: Faculty of Health School of Medicine   Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Thu, 10 Oct 2013, 10:14:43 EST Thu, 10 Oct 2013, 16:04:44 EST Tue, 15 Oct 2013, 08:42:49 EST Tue, 15 Oct 2013, 08:46:06 EST Tue, 15 Oct 2013, 08:47:06 EST Wed, 16 Oct 2013, 14:07:14 EST Thu, 15 May 2014, 09:49:01 EST Fri, 08 Aug 2014, 15:48:56 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 9 times in Scopus Search Google Scholar Access Statistics: 674 Abstract Views, 9 File Downloads  -  Detailed Statistics Created: Thu, 10 Oct 2013, 10:14:31 EST by Jane Moschetti