Aptamers as theranostic agents: modifications, serum stability and functionalisation Shigdar, Sarah, Macdonald, Joanna, O'Connor, Michael, Wang, Tao, Xiang, Dongxi, Al.Shamaileh, Hadi, Qiao, Liang, Wei, Ming, Zhou, Shu-Feng, Zhu, Yimin, Kong, Lingxue, Bhattacharya, Santanu, Li, ChunGuang and Duan, Wei 2013, Aptamers as theranostic agents: modifications, serum stability and functionalisation, Sensors, vol. 13, no. 10, pp. 13624-13637, doi: 10.3390/s131013624. Attached Files Name Description MIMEType Size Downloads shigdar-aptamersastheranostic-2013.pdf Published version application/pdf 646.07KB 231 Title Aptamers as theranostic agents: modifications, serum stability and functionalisation Author(s) Shigdar, Sarah orcid.org/0000-0001-8084-8447 Macdonald, Joanna O'Connor, Michael Wang, Tao Xiang, Dongxi Al.Shamaileh, Hadi Qiao, Liang Wei, Ming Zhou, Shu-Feng Zhu, Yimin Kong, Lingxue Bhattacharya, Santanu Li, ChunGuang Duan, Wei orcid.org/0000-0001-5782-9184 Journal name Sensors Volume number 13 Issue number 10 Start page 13624 End page 13637 Total pages 14 Publisher M D P I AG Place of publication Basel, Switzerland Publication date 2013-10 ISSN 1424-8239 1424-8220 Keyword(s) aptamer SELEX cancer diagnostics locked nucleic acid unlocked nucleic acid Summary Aptamers, and the selection process known as Systematic Evolution of Ligands by Exponential Enrichment (SELEX) used to generate them, were first described more than twenty years ago. Since then, there have been numerous modifications to the selectionprocedures. This review discusses the use of modified bases as a means of enhancing serum stability and producing effective therapeutic tools, as well as functionalising these nucleic acids to be used as potential diagnostic agents. Language eng DOI 10.3390/s131013624 Field of Research 111201 Cancer Cell Biology Socio Economic Objective 920102 Cancer and Related Disorders HERDC Research category C1 Refereed article in a scholarly journal Copyright notice ©2013, M D P I AG Free to Read? Yes Persistent URL http://hdl.handle.net/10536/DRO/DU:30059488 Document type: Journal Article Collections: Faculty of Health School of Medicine Institute for Frontier Materials Open Access Collection GTP Research Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Tue, 14 Jan 2014, 13:06:57 EST Wed, 15 Jan 2014, 10:31:45 EST Wed, 15 Jan 2014, 10:33:37 EST Thu, 16 Jan 2014, 10:10:16 EST Thu, 16 Jan 2014, 10:13:58 EST Thu, 16 Jan 2014, 10:17:50 EST Thu, 16 Jan 2014, 10:19:07 EST Thu, 16 Jan 2014, 15:00:58 EST Thu, 16 Jan 2014, 15:01:53 EST Fri, 14 Feb 2014, 13:53:32 EST Fri, 14 Feb 2014, 13:56:41 EST Fri, 13 Jun 2014, 19:28:43 EST Mon, 19 Jan 2015, 12:15:11 EST Tue, 08 Sep 2015, 13:57:26 EST Mon, 24 Apr 2017, 09:48:54 EST Wed, 06 Dec 2017, 10:40:04 EST Fri, 07 Sep 2018, 17:43:02 EST Filtered Full Citation counts:   Cited 85 times in TR Web of Science Cited 32 times in Scopus Search Google Scholar Access Statistics: 858 Abstract Views, 232 File Downloads  -  Detailed Statistics Created: Tue, 14 Jan 2014, 13:06:43 EST by Jane Moschetti