The International Society for Bipolar Disorders (ISBD) Task Force report on the nomenclature of course and outcome in bipolar disorders

Tohen, M., Frank, E., Bowden, C.L., Colom, F., Ghaemi, S.N., Yatham, L.N., Malhi, G.S., Calabrese, J.R., Nolen, W.A., Vieta, E., Kapczinski, F., Goodwin, G.M., Suppes, T., Sachs, G.S., Chengappa, K.N.R., Grunze, H., Mitchell, P.B., Kanba, S. and Berk, M. 2009, The International Society for Bipolar Disorders (ISBD) Task Force report on the nomenclature of course and outcome in bipolar disorders, Bipolar disorders, vol. 11, no. 5, pp. 453-473, doi: 10.1111/j.1399-5618.2009.00726.x.

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Title The International Society for Bipolar Disorders (ISBD) Task Force report on the nomenclature of course and outcome in bipolar disorders
Author(s) Tohen, M.
Frank, E.
Bowden, C.L.
Colom, F.
Ghaemi, S.N.
Yatham, L.N.
Malhi, G.S.
Calabrese, J.R.
Nolen, W.A.
Vieta, E.
Kapczinski, F.
Goodwin, G.M.
Suppes, T.
Sachs, G.S.
Chengappa, K.N.R.
Grunze, H.
Mitchell, P.B.
Kanba, S.
Berk, M.ORCID iD for Berk, M.
Journal name Bipolar disorders
Volume number 11
Issue number 5
Start page 453
End page 473
Total pages 21
Publisher Wiley
Place of publication London, Eng.
Publication date 2009-08
ISSN 1398-5647
Keyword(s) affective switch
bipolar disorder
course and outcome
functional outcome
predominant polarity
Summary Objectives:  Via an international panel of experts, this paper attempts to document, review, interpret, and propose operational definitions used to describe the course of bipolar disorders for worldwide use, and to disseminate consensus opinion, supported by the existing literature, in order to better predict course and treatment outcomes. Methods:  Under the auspices of the International Society for Bipolar Disorders, a task force was convened to examine, report, discuss, and integrate findings from the scientific literature related to observational and clinical trial studies in order to reach consensus and propose terminology describing course and outcome in bipolar disorders. Results:  Consensus opinion was reached regarding the definition of nine terms (response, remission, recovery, relapse, recurrence, subsyndromal states, predominant polarity, switch, and functional outcome) commonly used to describe course and outcomes in bipolar disorders. Further studies are needed to validate the proposed definitions. Conclusion:  Determination and dissemination of a consensus nomenclature serve as the first step toward producing a validated and standardized system to define course and outcome in bipolar disorders in order to identify predictors of outcome and effects of treatment. The task force acknowledges that there is limited validity to the proposed terms, as for the most part they represent a consensus opinion. These definitions need to be validated in existing databases and in future studies, and the primary goals of the task force are to stimulate research on the validity of proposed concepts and further standardize the technical nomenclature.
Language eng
DOI 10.1111/j.1399-5618.2009.00726.x
Field of Research 110319 Psychiatry (incl Psychotherapy)
Socio Economic Objective 920410 Mental Health
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2009, Wiley-Blackwell
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Document type: Journal Article
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School of Medicine
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