Layer-by-layer assembly of silica nanoparticles on 3D fibrous scaffolds : enhancement of osteoblast cell adhesion, proliferation, and differentiation Tang,Y, Zhao,Y, Wang,X and Lin,T 2014, Layer-by-layer assembly of silica nanoparticles on 3D fibrous scaffolds : enhancement of osteoblast cell adhesion, proliferation, and differentiation, Journal of Biomedical Materials Research - Part A, vol. 102, no. 11, pp. 3803-3812, doi: 10.1002/jbm.a.35050. Attached Files Name Description MIMEType Size Downloads Title Layer-by-layer assembly of silica nanoparticles on 3D fibrous scaffolds : enhancement of osteoblast cell adhesion, proliferation, and differentiation Author(s) Tang,Y Zhao,Y Wang,X orcid.org/0000-0002-3549-6769 Lin,T orcid.org/0000-0002-1003-0671 Journal name Journal of Biomedical Materials Research - Part A Volume number 102 Issue number 11 Start page 3803 End page 3812 Total pages 10 Publisher John Wiley & Sons Place of publication NJ, United States Publication date 2014-11-01 ISSN 1552-4965 Keyword(s) 3D scaffolds nanostructured surface osteoblasts tissue engineering Science & Technology Technology Engineering, Biomedical Materials Science, Biomaterials Engineering Materials Science NANOSTRUCTURED SURFACES PROGRESSIVE DEVELOPMENT BONE TITANIUM PHENOTYPE TOPOGRAPHY ROUGHNESS Summary Silica nanoparticles were applied onto the fiber surface of an interbonded three-dimensional polycaprolactone fibrous tissue scaffold by an electrostatic layer-by-layer self-assembly technique. The nanoparticle layer was found to improve the fiber wettability and surface roughness. Osteoblast cells were cultured on the fibrous scaffolds to evaluate the biological compatibility. The silica nanoparticle coated scaffold showed enhanced cell attachment, proliferation, and alkaline phosphatase activities. The overall results suggested that interbonded fibrous scaffold with silica nanoparticulate coating could be a promising scaffolding candidate for various applications in bone repair and regeneration. Language eng DOI 10.1002/jbm.a.35050 Field of Research 090301 Biomaterials 100706 Nanofabrication, Growth and Self Assembly Socio Economic Objective 970110 Expanding Knowledge in Technology HERDC Research category C1 Refereed article in a scholarly journal ERA Research output type C Journal article Copyright notice ©2014, John Wiley & Sons Persistent URL http://hdl.handle.net/10536/DRO/DU:30070029 Document type: Journal Article Collections: Institute for Frontier Materials GTP Research Related Links Link Description Connect to Elements publication management system Go to link with your DU access privileges   Connect to published version Go to link with your DU access privileges   Author URL Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Wed, 25 Feb 2015, 11:44:27 EST Fri, 27 Feb 2015, 14:28:41 EST Sat, 28 Feb 2015, 04:00:17 EST Sat, 28 Feb 2015, 05:07:12 EST Tue, 03 Mar 2015, 13:49:39 EST Tue, 03 Mar 2015, 13:58:13 EST Filtered Full Citation counts:   Cited 32 times in TR Web of Science Cited 36 times in Scopus Search Google Scholar Access Statistics: 824 Abstract Views, 2 File Downloads  -  Detailed Statistics Created: Fri, 27 Feb 2015, 14:28:40 EST