The potential utility of a staging model as a course specifier: a bipolar disorder perspective. Berk,M, Hallam,KT and McGorry,PD 2007, The potential utility of a staging model as a course specifier: a bipolar disorder perspective., Journal of Affective Disorders, vol. 100, no. 1-3, pp. 279-281, doi: 10.1016/j.jad.2007.03.007. Attached Files Name Description MIMEType Size Downloads Title The potential utility of a staging model as a course specifier: a bipolar disorder perspective. Author(s) Berk,M orcid.org/0000-0002-5554-6946 Hallam,KT McGorry,PD Journal name Journal of Affective Disorders Volume number 100 Issue number 1-3 Start page 279 End page 281 Publisher Elsevier Place of publication Netherlands Publication date 2007-06 ISSN 0165-0327 Keyword(s) Science & Technology Life Sciences & Biomedicine Clinical Neurology Psychiatry Neurosciences & Neurology PSYCHIATRY, SCI PSYCHIATRY, SSCI prodrome treatment resistance stages management early intervention 1ST-EPISODE INTERVENTIONS IMPAIRMENT SPECTRUM LITHIUM VOLUME Summary Staging models are widely used in clinical medicine, and offer an insight into the progressive nature of many disorders. In general, the earlier stages of illness may be associated with a better prognosis and a higher treatment response. Once chronicity is reached, more complex and invasive treatments may be required, and the utility of treatments may decline. There is evidence that treatment response is greatest in the early phases of the disorder. There is also a progressive social and psychological burden of ongoing illness. This is paralleled by the twin notions of neuroprotection, which is supported by increasing evidence that structural changes in the disorder may be progressive and reversible with algorithm appropriate treatment, and that of early intervention, which posits that the optimal window for intervention is early in the illness course. A staging model compliments existing and proposed classifications of bipolar disorder, adding a temporal dimension to a cross sectional view. It may inform treatment choice and prognosis, and could have utility as a course specifier. Language eng DOI 10.1016/j.jad.2007.03.007 Field of Research 0 Not Applicable Socio Economic Objective 0 Not Applicable HERDC Research category C1.1 Refereed article in a scholarly journal Copyright notice ©2007, Elsevier Persistent URL http://hdl.handle.net/10536/DRO/DU:30071264 Document type: Journal Article Collections: Faculty of Health School of Medicine Related Links Link Description Connect to published version Go to link with your DU access privileges   Author URL Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Wed, 18 Mar 2015, 09:46:55 EST Thu, 19 Mar 2015, 04:08:42 EST Thu, 19 Mar 2015, 05:11:26 EST Fri, 05 Jun 2015, 14:23:25 EST Fri, 05 Jun 2015, 14:24:17 EST Mon, 12 Oct 2015, 15:57:04 EST Filtered Full Citation counts:   Cited 117 times in TR Web of Science Cited 128 times in Scopus Search Google Scholar Access Statistics: 512 Abstract Views, 0 File Downloads  -  Detailed Statistics Created: Wed, 18 Mar 2015, 09:46:55 EST

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