Fluoxetine treatment of acral lick dermatitis in dogs: a placebo-controlled randomized double blind trial. Wynchank,D and Berk,M 1998, Fluoxetine treatment of acral lick dermatitis in dogs: a placebo-controlled randomized double blind trial., Depression and Anxiety, vol. 8, no. 1, pp. 21-23. Attached Files Name Description MIMEType Size Downloads Title Fluoxetine treatment of acral lick dermatitis in dogs: a placebo-controlled randomized double blind trial. Author(s) Wynchank,D Berk,M orcid.org/0000-0002-5554-6946 Journal name Depression and Anxiety Volume number 8 Issue number 1 Start page 21 End page 23 Publisher Wiley Place of publication UNITED STATES Publication date 1998 ISSN 1091-4269 Summary The aim of the study was to assess the efficacy and tolerability of fluoxetine treatment of acral lick dermatitis (ALD) in dogs and to investigate ALD as an animal model of obsessive-compulsive disorder (OCD). Sixty-three dogs with ALD were treated with fluoxetine 20 mg daily, or placebo, for 6 weeks. In the fluoxetine group, owners rated both appearance of the lesion (t = 10.2, df = 29, P < 0.0001) and licking behavior (t = 10.2, df = 29, P < 0.0001) as significantly improved by the end of the trial. Veterinarian-rated pre- and post-treatment photographs showed statistically significant improvement in the fluoxetine group (mean = 2.55). There were no significant changes in the placebo group as rated by owners and veterinarians. These results demonstrate the efficacy of fluoxetine in the treatment of ALD and lend further support to ALD as an animal model of OCD. Language eng Field of Research 0 Not Applicable Socio Economic Objective 0 Not Applicable HERDC Research category C1.1 Refereed article in a scholarly journal Copyright notice ©1998, Wiley Persistent URL http://hdl.handle.net/10536/DRO/DU:30071422 Document type: Journal Article Collections: Faculty of Health School of Medicine Related Links Link Description Author URL Go to link with your DU access privileges   Connect to Elements publication management system Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Wed, 18 Mar 2015, 11:05:52 EST Thu, 19 Mar 2015, 04:20:41 EST Thu, 19 Mar 2015, 05:18:48 EST Tue, 09 Jun 2015, 16:59:28 EST Tue, 09 Jun 2015, 17:00:18 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 0 times in Scopus Search Google Scholar Access Statistics: 629 Abstract Views, 0 File Downloads  -  Detailed Statistics Created: Wed, 18 Mar 2015, 11:05:52 EST