Online mindfulness-based intervention for late-stage bipolar disorder: pilot evidence for feasibility and effectiveness

Murray, G., Leitan, N.D., Berk, M., Thomas, N., Michalak, E., Berk, L., Johnson, S.L., Jones, S., Perich, T., Allen, N.B. and Kyrios, M. 2015, Online mindfulness-based intervention for late-stage bipolar disorder: pilot evidence for feasibility and effectiveness, Journal of affective disorders, vol. 178, pp. 46-51, doi: 10.1016/j.jad.2015.02.024.

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Title Online mindfulness-based intervention for late-stage bipolar disorder: pilot evidence for feasibility and effectiveness
Author(s) Murray, G.
Leitan, N.D.
Berk, M.ORCID iD for Berk, M.
Thomas, N.
Michalak, E.
Berk, L.
Johnson, S.L.
Jones, S.
Perich, T.
Allen, N.B.
Kyrios, M.
Journal name Journal of affective disorders
Volume number 178
Start page 46
End page 51
Total pages 6
Publisher Elsevier
Place of publication Amsterdam, The Netherlands
Publication date 2015
ISSN 1573-2517
Keyword(s) Bipolar disorder
Quality of life
Science & Technology
Life Sciences & Biomedicine
Clinical Neurology
Neurosciences & Neurology
Summary OBJECTIVES: People in the late stage of bipolar disorder (BD) experience elevated relapse rates and poorer quality of life (QoL) compared with those in the early stages. Existing psychological interventions also appear less effective in this group. To address this need, we developed a new online mindfulness-based intervention targeting quality of life (QoL) in late stage BD. Here, we report on an open pilot trial of ORBIT (online, recovery-focused, bipolar individual therapy). METHODS: Inclusion criteria were: self-reported primary diagnosis of BD, six or more episodes of BD, under the care of a medical practitioner, access to the internet, proficient in English, 18-65 years of age. Primary outcome was change (baseline - post-treatment) on the Brief QoL.BD (Michalak and Murray, 2010). Secondary outcomes were depression, anxiety, and stress measured on the DASS scales (Lovibond and Lovibond, 1993). RESULTS: Twenty-six people consented to participate (Age M=46.6 years, SD=12.9, and 75% female). Ten participants were lost to follow-up (38.5% attrition). Statistically significant improvement in QoL was found for the completers, t(15)=2.88, 95% CI:.89-5.98, p=.011, (Cohen׳s dz=.72, partial η(2)=.36), and the intent-to-treat sample t(25)=2.65, 95% CI:.47-3.76, (Cohen׳s dz=.52; partial η(2)=.22). A non-significant trend towards improvement was found on the DASS anxiety scale (p=.06) in both completer and intent-to-treat samples, but change on depression and stress did not approach significance. LIMITATIONS: This was an open trial with no comparison group, so measured improvements may not be due to specific elements of the intervention. Structured diagnostic assessments were not conducted, and interpretation of effectiveness was limited by substantial attrition. CONCLUSION: Online delivery of mindfulness-based psychological therapy for late stage BD appears feasible and effective, and ORBIT warrants full development. Modifications suggested by the pilot study include increasing the 3 weeks duration of the intervention, adding cautions about the impact of extended meditations, and addition of coaching support/monitoring to optimise engagement.
Language eng
DOI 10.1016/j.jad.2015.02.024
Field of Research 110319 Psychiatry (incl Psychotherapy)
Socio Economic Objective 920410 Mental Health
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2015, Elsevier
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Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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