Dietary sources, current intakes, and nutritional role of omega-3 docosapentaenoic acid Byelashov, Oleksabdr A., Sinclair, Andrew J. and Kaur, Gunveen 2015, Dietary sources, current intakes, and nutritional role of omega-3 docosapentaenoic acid, Lipid technology, vol. 27, no. 4, pp. 79-82, doi: 10.1002/lite.201500013. Attached Files Name Description MIMEType Size Downloads Title Dietary sources, current intakes, and nutritional role of omega-3 docosapentaenoic acid Author(s) Byelashov, Oleksabdr A. Sinclair, Andrew J. Kaur, Gunveen orcid.org/0000-0002-6250-0495 Journal name Lipid technology Volume number 27 Issue number 4 Start page 79 End page 82 Total pages 4 Publisher Wiley Place of publication London, Eng. Publication date 2015-04 ISSN 0956-666X 1863-5377 Summary Fish oils and long-chain omega-3 fatty acids are well recognized for their critical role in human diets. Docosapentaenoic acid (DPA, 22:5n-3) has always been a part of healthy nutrition, since infants obtain almost as much DPA as DHA from human milk. Fish oil supplements and ingredients, oily fish, and grass-fed beef can serve as the primary DPA sources for the general population. Although the DPA levels in fish oils are substantially lower than those of EPA and DHA, concentrated DPA products are now becoming commercially available, and DPA-based drugs are under development. Epidemiological studies show that similar to eicosapentaenoic (EPA, 20:5n-3) and docosahexaenoic (DHA, 22:6n-3) acids, DPA is linked to various improvements in human health, perhaps owing to its structural similarity to the other two molecules. Studies in mammals, platelets, and cell cultures have demonstrated that DPA reduces platelet aggregation, and improves lipid metabolism, endothelial cell migration, and resolution of chronic inflammation. Further, other in vivo and in vitro studies have shown that DPA can improve neural health. A human supplementation trial with 99.8% pure DPA suggested that it serves as a storage depot for EPA and DHA in the human body. Future randomized controlled human trials with purified DPA will help clarify its effects on human health. They may confirm the available evidence pointing to its nutritional and biological functions, unique or overlapping with those of EPA and DHA. Language eng DOI 10.1002/lite.201500013 Field of Research 111199 Nutrition and Dietetics not elsewhere classified Socio Economic Objective 920411 Nutrition HERDC Research category C1 Refereed article in a scholarly journal ERA Research output type C Journal article Copyright notice ©2015, Wiley Persistent URL http://hdl.handle.net/10536/DRO/DU:30075768 Document type: Journal Article Collections: Faculty of Health School of Exercise and Nutrition Sciences School of Medicine Institute for Physical Activity and Nutrition Related Links Link Description Connect to published version Go to link with your DU access privileges   Connect to Elements publication management system Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Thu, 20 Aug 2015, 13:36:14 EST Thu, 20 Aug 2015, 15:05:33 EST Fri, 21 Aug 2015, 05:04:23 EST Fri, 21 Aug 2015, 06:09:18 EST Wed, 02 Sep 2015, 13:42:45 EST Wed, 02 Sep 2015, 13:43:54 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 69 times in Scopus Search Google Scholar Access Statistics: 491 Abstract Views, 4 File Downloads  -  Detailed Statistics Created: Thu, 20 Aug 2015, 15:05:33 EST