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Mechanisms and treatment of cardiac atrophy secondary to cancer cachexia

Hinch, Edward 2014, Mechanisms and treatment of cardiac atrophy secondary to cancer cachexia, Ph.D. thesis, School of Medicine, Deakin University.

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Title Mechanisms and treatment of cardiac atrophy secondary to cancer cachexia
Author Hinch, Edward
Institution Deakin University
School School of Medicine
Faculty Faculty of Health
Degree type Research doctorate
Degree name Ph.D.
Thesis advisor Lewandowski, Paul
Date submitted 2014-05
Keyword(s) cardiac tissue wastage
cancer cachexia
protein breakdown
Summary  This project found that oxidative stress and activation of pro-inflammatory molecules is a feature of heart protein loss secondary to cancer wasting. Treatment with an omega-3 fatty acid is able to protect against heart muscle loss in cancer by reducing gene transcripts of both pro-inflammatory and oxidative molecules.
Language eng
Field of Research 110201 Cardiology (incl Cardiovascular Diseases)
Socio Economic Objective 920102 Cancer and Related Disorders
Description of original xiv, 165 pages : illustrations, tables, graphs
Copyright notice ©The Author. All Rights Reserved
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30079107

Document type: Thesis
Collections: Higher degree theses (Open Access)
Open Access Collection
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Created: Sun, 25 Oct 2015, 15:25:53 EST by Kate Percival

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.