Corticomotor excitability is increased following an acute bout of blood flow restriction resistance exercise

Brandner, Christopher, Warmington, Stuart and Kidgell, Dawson 2015, Corticomotor excitability is increased following an acute bout of blood flow restriction resistance exercise, Frontiers in human neuroscience, vol. 9, no. 652, pp. 1-10.

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Title Corticomotor excitability is increased following an acute bout of blood flow restriction resistance exercise
Author(s) Brandner, Christopher
Warmington, StuartORCID iD for Warmington, Stuart
Kidgell, Dawson
Journal name Frontiers in human neuroscience
Volume number 9
Issue number 652
Start page 1
End page 10
Total pages 10
Publisher Frontiers Media
Place of publication Lausanne, Switzerland
Publication date 2015-12-02
ISSN 1662-5161
Keyword(s) Transcranial Magnetic Stimulation
strength training
intracortical inhibition
motor cortex plasticity
vascular occlusion
Summary We used transcranial magnetic stimulation (TMS) to investigate whether an acute bout of resistance exercise with blood flow restriction (BFR) stimulated changes in corticomotor excitability (motor evoked potential, MEP) and short-interval intracortical inhibition (SICI), and compared the responses to two traditional resistance exercise methods. Ten males completed four unilateral elbow flexion exercise trials in a balanced, randomized crossover design: (1) heavy-load (HL: 80% one-repetition maximum [1-RM]); (2) light-load (LL; 20% 1-RM) and two other light-load trials with BFR applied; (3) continuously at 80% resting systolic blood pressure (BFR-C); or (4) intermittently at 130% resting systolic blood pressure (BFR-I). MEP amplitude and SICI were measured using TMS at baseline, and at four time-points over a 60 min post-exercise period. MEP amplitude increased rapidly (within 5 min post-exercise) for BFR-C and remained elevated for 60 min post-exercise compared with all other trials. MEP amplitudes increased for up to 20 and 40 min for LL and BFR-I, respectively. These findings provide evidence that BFR resistance exercise can modulate corticomotor excitability, possibly due to altered sensory feedback via group III and IV afferents. This response may be an acute indication of neuromuscular adaptations that underpin changes in muscle strength following a BFR resistance training programme.
Language eng
Field of Research 110699 Human Movement and Sports Science not elsewhere classified
Socio Economic Objective 929999 Health not elsewhere classified
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2015, Frontiers Media
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Document type: Journal Article
Collections: Faculty of Health
School of Exercise and Nutrition Sciences
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