Can cancer therapy be achieved by bridging apoptosis and autophagy: A method based on microRNA-dependent gene therapy and phytochemical targets Vijayarathna, Soundararajan, Gothai, Sivapragasam, Jothy, Subramanion L., Chen, Yeng, Kanwar, Jagat R. and Sasidharan, Sreenivasan 2015, Can cancer therapy be achieved by bridging apoptosis and autophagy: A method based on microRNA-dependent gene therapy and phytochemical targets, Asian pacific journal of cancer prevention, vol. 16, no. 17, pp. 7435-7439, doi: 10.7314/APJCP.2015.16.17.7435. Attached Files Name Description MIMEType Size Downloads kanwar-cancancer-2015.pdf Published version application/pdf 3.42MB 112 Title Can cancer therapy be achieved by bridging apoptosis and autophagy: A method based on microRNA-dependent gene therapy and phytochemical targets Author(s) Vijayarathna, Soundararajan Gothai, Sivapragasam Jothy, Subramanion L. Chen, Yeng Kanwar, Jagat R. orcid.org/0000-0003-3728-9568 Sasidharan, Sreenivasan Journal name Asian pacific journal of cancer prevention Volume number 16 Issue number 17 Start page 7435 End page 7439 Total pages 5 Publisher Asian Pacific Education Press Place of publication Bangkok, Asia Publication date 2015-01-01 ISSN 1513-7368 Keyword(s) Autophagy apoptosis microRNAs natural remedies Summary A failure of a cell to self destruct has long been associated with cancer progression and development. The fact that tumour cells may not instigate cell arrest or activate cell death mechanisms upon cancer drug delivery is a major concern. Autophagy is a mechanism whereby cell material can be engulfed and digested while apoptosis is a self-killing mechanism, both capable of hindering multiplication after cell injury. In particular situations, autophagy and apoptosis seem to co-exist simultaneously or interdependently with the aid of mutual proteins. This review covers roles of microRNAs and chemopreventive agents and makes an attempt at outlining possible partnerships in maximizing cancer cell death with minimal normal cell damage. Language eng DOI 10.7314/APJCP.2015.16.17.7435 Field of Research 1112 Oncology And Carcinogenesis 1117 Public Health And Health Services Socio Economic Objective 920102 Cancer and Related Disorders HERDC Research category C1 Refereed article in a scholarly journal Copyright notice ©2015, Asian Pacific Education Press Free to Read? Yes Persistent URL http://hdl.handle.net/10536/DRO/DU:30080757 Document type: Journal Article Collections: Faculty of Health School of Medicine Open Access Collection Related Links Link Description Connect to Elements publication management system Go to link with your DU access privileges   Connect to published version Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Mon, 18 Jan 2016, 09:03:30 EST Tue, 19 Jan 2016, 04:00:26 EST Tue, 19 Jan 2016, 05:25:30 EST Mon, 21 Mar 2016, 12:38:56 EST Mon, 21 Mar 2016, 12:39:50 EST Wed, 23 Mar 2016, 07:39:56 EST Wed, 07 Sep 2016, 11:04:55 EST Wed, 06 Dec 2017, 06:49:40 EST Fri, 07 Sep 2018, 17:40:42 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 4 times in Scopus Search Google Scholar Access Statistics: 632 Abstract Views, 114 File Downloads  -  Detailed Statistics Created: Mon, 18 Jan 2016, 09:03:30 EST