Increasing body weight and risk of limitations in activities of daily living: a systematic review and meta-analysis

Backholer, K., Wong, E., Freak-Poli, R., Walls, H. L. and Peeters, A. 2012, Increasing body weight and risk of limitations in activities of daily living: a systematic review and meta-analysis, Obesity reviews, vol. 13, no. 5, pp. 456-468, doi: 10.1111/j.1467-789X.2011.00970.x.

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Title Increasing body weight and risk of limitations in activities of daily living: a systematic review and meta-analysis
Author(s) Backholer, K.ORCID iD for Backholer, K.
Wong, E.
Freak-Poli, R.
Walls, H. L.
Peeters, A.ORCID iD for Peeters, A.
Journal name Obesity reviews
Volume number 13
Issue number 5
Start page 456
End page 468
Total pages 13
Publisher Wiley
Place of publication London, Eng.
Publication date 2012-05
ISSN 1467-789X
Keyword(s) Activities of Daily Living
Body Mass Index
Cost of Illness
Disabled Persons
Severity of Illness Index
Weight Gain
Science & Technology
Life Sciences & Biomedicine
Endocrinology & Metabolism
Summary This study examined the relationship between normal weight, overweight and obesity class I and II+, and the risk of disability, which is defined as impairment in activities of daily living (ADL). Systematic searching of the literature identified eight cross-sectional studies and four longitudinal studies that were comparable for meta-analysis. An additional four cross-sectional studies and one longitudinal study were included for qualitative review. Results from the meta-analysis of cross-sectional studies revealed a graded increase in the risk of ADL limitations from overweight (1.04, 95% confidence interval [CI] 1.00-1.08), class I obesity (1.16, 95% CI 1.11-1.21) and class II+ obesity (1.76, 95% CI 1.28-2.41), relative to normal weight. Meta-analyses of longitudinal studies revealed a similar graded relationship; however, the magnitude of this relationship was slightly greater for all body mass index categories. Qualitative analysis of studies that met the inclusion criteria but were not compatible for meta-analysis supported the pooled results. No studies identified met all of the pre-defined quality criteria, and subgroup analysis was inhibited due to insufficient comparable studies. We conclude that increasing body weight increases the risk of disability in a graded manner, but also emphasize the need for additional studies using contemporary longitudinal cohorts with large numbers of obese class III individuals, a range of ages and with measured height and weight, and incident ADL questions.
Language eng
DOI 10.1111/j.1467-789X.2011.00970.x
Field of Research 111799 Public Health and Health Services not elsewhere classified
Socio Economic Objective 920499 Public Health (excl. Specific Population Health) not elsewhere classified
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2011, International Association for the Study of Obesity
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Document type: Journal Article
Collections: Faculty of Health
School of Health and Social Development
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