Antidepressant mechanisms of deep brain stimulation for treatment resistant depression Kim, Yesul 2015, Antidepressant mechanisms of deep brain stimulation for treatment resistant depression, Ph.D. thesis, School of Psychology, Deakin University. Attached Files Name Description MIMEType Size Downloads kim-antidepressantmechanisms-2016A.pdf Connect to thesis application/pdf 15.58MB 228 Title Antidepressant mechanisms of deep brain stimulation for treatment resistant depression Author Kim, Yesul Institution Deakin University School School of Psychology Faculty Faculty of Health Degree type Research doctorate Degree name Ph.D. Thesis advisor Byrne, Linda orcid.org/0000-0001-9055-0046 Tye, Susannah Date submitted 2015 Keyword(s) deep brain stimulation (DBS) treatment resistant depression (TRD) antidepressants Summary Deep brain stimulation to clinically relevant brain targets all produced therapeutic responses in an animal model of antidepressant resistance. Such effects were achieved by modulating cellular stress, impaired synaptic plasticity, dysregulated dopamine transmission and energy metabolism. The implication of these findings underscore the need for using appropriate animal models to gain valuable insight on the neurobiological state of the organism in health and disease. Language eng Field of Research 110319 Psychiatry (incl Psychotherapy) 110903 Central Nervous System Socio Economic Objective 920111 Nervous System and Disorders Description of original 303 pages : illustrations, tables, figures, appendices Copyright notice ©The Author. All Rights Reserved Free to Read? Yes Persistent URL http://hdl.handle.net/10536/DRO/DU:30085500 Document type: Thesis Collections: Higher degree theses (Open Access) Open Access Collection   Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Wed, 17 Aug 2016, 16:14:05 EST Thu, 18 Aug 2016, 08:45:34 EST Tue, 11 Oct 2016, 12:19:53 EST Tue, 11 Oct 2016, 12:22:26 EST Tue, 11 Oct 2016, 13:01:02 EST Tue, 11 Oct 2016, 14:51:08 EST Wed, 12 Oct 2016, 07:45:59 EST Fri, 25 Nov 2016, 09:51:20 EST Thu, 09 Mar 2017, 07:24:31 EST Thu, 09 Mar 2017, 09:21:14 EST Tue, 31 Jul 2018, 15:24:38 EST Fri, 07 Sep 2018, 18:54:44 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 0 times in Scopus Search Google Scholar Access Statistics: 256 Abstract Views, 238 File Downloads  -  Detailed Statistics Created: Wed, 17 Aug 2016, 16:13:54 EST by Prue Plummer