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Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene

Hermans, Mirjam H. A., Antonissen, Claudia, Ward, Alister C., Mayen, Angelique E. M., Ploemacher, Rob E. and Touw, Ivo P. 1999, Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene, Journal of Experimental Medicine, vol. 189, no. 4, pp. 683-692, doi: 10.1084/jem.189.4.683.

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Title Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene
Author(s) Hermans, Mirjam H. A.
Antonissen, Claudia
Ward, Alister C.ORCID iD for Ward, Alister C. orcid.org/0000-0001-7945-7975
Mayen, Angelique E. M.
Ploemacher, Rob E.
Touw, Ivo P.
Journal name Journal of Experimental Medicine
Volume number 189
Issue number 4
Start page 683
End page 692
Total pages 9
Publisher Rockefeller University Press
Place of publication New York, N.Y.
Publication date 1999-02-15
ISSN 0022-1007
Keyword(s) Acute Disease
Animals
Bone Marrow
Cell Differentiation
Cell Division
Cell Transformation, Neoplastic
Colony-Forming Units Assay
DNA-Binding Proteins
Endocytosis
Granulocyte Colony-Stimulating Factor
Hematopoietic Stem Cells
Humans
Immunologic Deficiency Syndromes
Kinetics
Leukemia, Myeloid
Lymphocyte Activation
Mice
Mice, Transgenic
Milk Proteins
Neutropenia
Receptors, Granulocyte Colony-Stimulating Factor
STAT1 Transcription Factor
STAT5 Transcription Factor
Sequence Deletion
Specific Pathogen-Free Organisms
Trans-Activators
severe congenital neutropenia
granulocyte colony-stimulating factor receptor
mutations
acute myeloid leukemia
Language eng
DOI 10.1084/jem.189.4.683
Field of Research 11 Medical And Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©1999, Rockefeller University Press
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30088504

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
Open Access Collection
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.